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Displaying results 2751 - 2760 of 8171 in total
  1. Drug

    Purslane

    go.drugbank.com/drugs/DB14327
    Approved

    It is not an approved drug.

  2. Drug

    Seproxetine

    go.drugbank.com/drugs/DB06731
    Experimental

    It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.

    Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  3. Drug

    Thioredoxin

    go.drugbank.com/drugs/DB11298
    Approved

    It plays an essential role as an antioxidant in neutralizing food allergens and redox signalling. Allergens containing disulfide bonds are inactivated when reduced by thioredoxin.

  4. Drug

    Trastuzumab botidotin

    go.drugbank.com/drugs/DB17413
    Experimental

    A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable

  5. Drug

    Dichlorotetrafluoroethane

    go.drugbank.com/drugs/DB20118
    ApprovedWithdrawn

    Dichlorotetrafluoroethane has a monoisotopic molecular weight of 169.93 Da.

  6. Drug

    Iopydone

    go.drugbank.com/drugs/DB20831
    ApprovedWithdrawn

    Iopydone has a monoisotopic molecular weight of 346.83 Da.

  7. Drug

    Crizanlizumab

    go.drugbank.com/drugs/DB15271
    ApprovedInvestigational

    Sickle cell disease can lead to excruciating pain, stroke, infection, and various other complications arising from the blockage of blood vessels. … [L10097] While crizanlizumab received conditional marketing authorization from the EMA in October 2020, this approval was revoked in August 2023 due to concerns over the efficacy and safety of the drug

  8. Drug

    Etomidate

    go.drugbank.com/drugs/DB00292
    ApprovedInvestigational

    It has been proposed as an induction anesthetic.

  9. Drug

    Idarubicin

    go.drugbank.com/drugs/DB01177
    ApprovedInvestigational

    An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: IDARALEM RU
  10. Drug

    Chlorphenoxamine

    go.drugbank.com/drugs/DB09007
    ApprovedWithdrawn

    It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.

    Synonyms: 2-((P-CHLORO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINE