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Flucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Categories: Antifungals for Topical Use, Antimycotics for Systemic UseEtafedrine
go.drugbank.com/drugs/DB11587ApprovedEtafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. … The hydrochloride is be prepared by passing hydrogen chloride through a solution of ethylephedrine in diethyl ether [F6]. This belongs to the family of medications called _decongestants_.
Thalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnIt has been reintroduced and used for a number of inflammatory disorders and cancers. … A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects.
Synonyms: N-Phthaloylglutamimide, α-N-phthalylglutaramideInternational brands: Pro-ban MCyclopentolate
go.drugbank.com/drugs/DB00979ApprovedA parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Products: CICLOPENTOLATO AL 1 %Palifermin
go.drugbank.com/drugs/DB00039ApprovedInvestigationalPalifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.[L17933]
Categories: Detoxifying Agents for Antineoplastic TreatmentBrivudine
go.drugbank.com/drugs/DB03312ApprovedInvestigationalBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSynonyms: (E)-5-(2-Bromovinyl)-deoxyuridineHexachlorophene
go.drugbank.com/drugs/DB00756ApprovedWithdrawnIt is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) … A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms.
International brands: E-Z scrub, Surgi-CenPegaptanib
go.drugbank.com/drugs/DB04895ApprovedWithdrawnPegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. … Pegaptanib was granted FDA approval on 17 September 2004.[L17903]
Categories: Vascular Endothelial Growth Factor ACefpirome
go.drugbank.com/drugs/DB13682ApprovedCefpirome is a β-lactam or cephalosporin.[A249055]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use