Cyclopentolate

DB00979ApprovedSmall moleculeMuscarinic AntagonistsMydriatics

Cyclopentolate is an anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing. A medication used to dilate pupils for examination of the eye.

Chemical structure of Cyclopentolate
Mechanism
Curator reviewed
Primary indication
Used mainly to produce mydriasis and cycloplegia for diagnostic purposes.Curator reviewed · 4 structured indications
Formula / weight
C17H25NO3 · 291.3853 g/mol (avg)
First approval
Canada, 2015 · United States, 1958
Brand names
  • Ak-pentolate
  • Cyclogyl
  • Cyclomydril
  • Minims Cyclopentolate Hydrochloride

Resolves to

Compound
UNIII76F4SHP7JCAS512-15-2ChEMBLCHEMBL1201338ChEBI4024PubChem2905KEGGC06932
Clinical / RWD
RxNorm3001ATCS01FA04ATCS01FA54PharmGKBPA164743019
Structure
InChIKeySKYSRIRYMSLOIN-UHFFFAOYSA-NSMILESCN(C)CCOC(=O)C(C1=CC=CC=C1)C1(O)CCCC1
Targets
P20309CHRM3P11229CHRM1P08912CHRM5

What you can answer from here — as of September 12, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
232Drug interactionsStructured to mechanism, not free text
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13Clinical trialsPhase, status and sponsor resolved per trial
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4Structured indicationsCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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43Marketed productsAcross 10 countries and 23 labellers
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2ATC codesIncluding every combination product, plus 14 drug categories
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11+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Cyclopentolate, and which of those have an active Phase 3 trial?

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