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Methoxsalen
go.drugbank.com/drugs/DB00553ApprovedInvestigationalA naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Categories: Antipsoriatics for Systemic Use, Antipsoriatics for Topical UserhThrombin
go.drugbank.com/drugs/DB04923ApprovedWithdrawnZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. … The production of recombinant proteins is not dependent on the availability of blood from animals or human donors and can be scaled-up to meet market demand.
Potassium cation
go.drugbank.com/drugs/DB01345ApprovedThe ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function.
Gadofosveset trisodium
go.drugbank.com/drugs/DB06705ApprovedThe agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels.
Categories: Compounds used in a research, industrial, or household settingTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalIn dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Categories: Antihistamines for Systemic UseAcenocoumarol
go.drugbank.com/drugs/DB01418ApprovedInvestigationalAcenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and ...
Monobenzone
go.drugbank.com/drugs/DB00600ApprovedWithdrawnMonobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation.
Poractant alfa
go.drugbank.com/drugs/DB09113ApprovedInvestigationalPoractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alf...
Terfenadine
go.drugbank.com/drugs/DB00342ApprovedWithdrawnIn the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Categories: Antihistamines for Systemic UseRacepinephrine
go.drugbank.com/drugs/DB11124ApprovedRacepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermitt...