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Osilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigationalOsilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes the final step in the biosynthesis of endogenous cortisol. It is used to lower circulating cortisol levels in the treatment of Cushi...
Categories: Sex Hormones and InsulinsWIN 55212-2
go.drugbank.com/drugs/DB13950ExperimentalWIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabino...
Categories: Membrane Transport ModulatorsNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigationalNortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Categories: Membrane Transport ModulatorsDihydromorphine
go.drugbank.com/drugs/DB01565ExperimentalIllicitA semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Categories: Semi-synthetic OpioidsHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnCertain population subgroups in these areas, however, are at high risk (see Indications and Clinical Use). … The incubation period may be as long as 6 months, followed by a very complex clinical course of an acute or chronic nature, often leading to hospitalization.
Categories: Complex MixturesDental Mesenchymal Pulp Stem Cells
go.drugbank.com/drugs/DB15737InvestigationalDental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties.
Synonyms: Dental Pulp Mesenchymal Stem Cells, Allogenic Human Dental Pulp Stem CellsRetinol dehydrogenase 11
go.drugbank.com/bio_entities/BE0002321TargetHumansRetinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12036956, PubMed:12226107, PubMed:29410696). Exhibits a low redu...
Synonyms: HCV core-binding protein HCBP12Celecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigationalCelecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other
Categories: Genito Urinary System and Sex HormonesMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigationalMethimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those f...
Categories: Sex Hormones and Insulins