Search

Displaying results 2771 - 2780 of 10000 in total
  1. Drug

    Tesmilifene

    go.drugbank.com/drugs/DB04905
    Investigational

    Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast

    Synonyms: N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamineCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  2. Drug

    Famphur

    go.drugbank.com/drugs/DB11408
    ExperimentalVet approved

    Synonyms: O-[4-(dimethylsulfamoyl)phenyl] O,O-dimethyl thiophosphate, Phosphorothioic acid, O-(4-((dimethylamino)sulfonyl)phenyl) O,O-dimethyl esterCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide

    go.drugbank.com/drugs/DB07875
    Experimental

    Synonyms: 5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide
  4. Drug

    Moricizine

    go.drugbank.com/drugs/DB00680
    ApprovedWithdrawn

    An antiarrhythmia agent used primarily for ventricular rhythm disturbances.

    Synonyms: ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate, [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl esterCategories: Antiarrhythmics, Class I, Heterocyclic Compounds, 1-Ring
  5. Drug

    Lovastatin

    go.drugbank.com/drugs/DB00227
    ApprovedInvestigational

    were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%. … [A174553] More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid

    Synonyms: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactoneCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  6. Drug

    Piceatannol

    go.drugbank.com/drugs/DB08399
    Experimental

    Synonyms: 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol, 3,5,3',4'-tetrahydroxystilbene
  7. Drug

    (4R)-limonene

    go.drugbank.com/drugs/DB08921
    Investigational

    As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant … in perfumery.

    Synonyms: (4R)-1-methyl-4-isopropenylcyclohex-1-ene, (4R)-4-isopropenyl-1-methylcyclohexene
  8. Drug

    PF-4136309

    go.drugbank.com/drugs/DB17200
    Investigational

    Synonyms: Benzamide, n-(2-((3s)-3-((trans-4-hydroxy-4-(5-(2-pyrimidinyl)- 2-pyridinyl)cyclohexyl)amino)-1-pyrrolidinyl)-2-oxoethyl)-3-(trifluoromethyl)-, N-(2-((3s)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2- yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamideCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Arcitumomab

    go.drugbank.com/drugs/DB17201
    Experimental

    Synonyms: Immunoglobulin g 1 (mouse monoclonal immu-4 fab' fragment .gamma.-chain anti-human antigen cea), disulfide with mouse monoclonal immu-4 light chain, Immunoglobulin g 1 (mouse monoclonal immu-4 fab' fragment .gamma.-chain anti-human antigen cea), disulphide with mouse monoclonal immu-4 light chain
  10. Drug

    Bis(2,2-dimethylpropanoyloxymethyl) VK-0214

    go.drugbank.com/drugs/DB17876
    Experimental

    Synonyms: 2,2-dimethylpropanoic acid 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy)methyl)phosphinylidene)bis(oxymethylene)) ester, Propanoic acid, 2,2-dimethyl-, 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy)methyl)phosphinylidene)bis(oxymethylene)) ester