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T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
go.drugbank.com/conditions/DBCOND0082251Drugs: Polatuzumab vedotinSynonyms: Malignant lymphoma, large cell, cleaved and noncleaved, Malignant lymphoma - large cell cleaved and non-cleavedPeginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalPeginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by binding to human type 1 interferon receptors. … Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsRubella virus vaccine
go.drugbank.com/drugs/DB10317ApprovedInvestigationalIt is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Mixtures: MEASLES AND RUBELLA VIRUS VACCINE LIVE, SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 doseCategories: measles, combinations with mumps and rubella, live attenuated, measles, combinations with mumps, rubella and varicella, live attenuatedAcetohexamide
go.drugbank.com/drugs/DB00414ApprovedWithdrawnAcetohexamide has been discontinued in the US market.
Categories: Alimentary Tract and Metabolism, Genito Urinary System and Sex HormonesReviparin
go.drugbank.com/drugs/DB09259Approved[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469] … [A32019] It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa.
Categories: Heparin and similars, Blood and Blood Forming OrgansLipegfilgrastim
go.drugbank.com/drugs/DB13200ApprovedNeutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur from myelosuppressive anticancer treatments [A32665]. … PEG moiety protects the active molecule from enzyme degradation, which allows longer half-life of drug and less frequent dosing-schedule in addition to acceptable safety and efficacy profile [A32665].
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsPyruvic acid
go.drugbank.com/drugs/DB00119ApprovedInvestigationalNutraceutical(From Stedman, 26th ed) … An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures.
Tubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawn[A216008] Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of … [A216038] Tubocurarine's clinical use was limited by its relatively long duration of action (30-60 minutes)[A216038] and a number of significant side effects.
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
go.drugbank.com/bio_entities/BE0000059TargetEnzymeHumans3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.
Synonyms: 3-beta-HSD adrenal and gonadal typeP-type Ca(2+) transporter
go.drugbank.com/bio_entities/BE0009164TargetPlasmodium falciparumSynonyms: Sarcoplasmic and endoplasmic reticulum Ca-ATPase