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Displaying results 271 - 280 of 10000 in total
  1. Drug

    EW-A-401

    go.drugbank.com/drugs/DB05525
    Investigational

    EW-A-401 is a circle of genetic material (plasmid DNA) that instructs the body to produce a genetically-engineered transcription factor, a protein that regulates expression of genes. … This specific transcription factor has been shown in animal studies to increase expression of the VEGF-A gene, and to promote the growth of new blood vessels.

    Synonyms: EW-A-401 DNA Plasmid Vector
  2. Drug

    Salvianolic acid A

    go.drugbank.com/drugs/DB15246
    Investigational

    Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).

    Synonyms: Salvianolic acid A
  3. Drug

    10-decarboxymethylaclacinomycin A

    go.drugbank.com/drugs/DB01806
    Experimental

    Synonyms: 10-decarboxymethylaclacinomycin A
  4. Drug

    Trifluoroacetonyl coenzyme A

    go.drugbank.com/drugs/DB01969
    Experimental

    Synonyms: Trifluoroacetonyl coenzyme A
  5. Drug

    Feruloyl Coenzyme A

    go.drugbank.com/drugs/DB03923
    Experimental

    Synonyms: Feruloyl Coenzyme A
  6. Drug

    Zaleplon

    go.drugbank.com/drugs/DB00962
    ApprovedIllicit

    Zaleplon is a schedule IV drug in the United States. … Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic.

    Synonyms: 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilideCategories: GABA-A Receptor Agonists, gamma-Aminobutyric Acid A Receptor Agonist
  7. Drug

    Atidarsagene autotemcel

    go.drugbank.com/drugs/DB17538
    ApprovedInvestigational

    [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic … a lentiviral vector encoding the human arylsulfatase A (ARSA) gene.

    Synonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene, Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid sequence
  8. Drug

    Cyclobenzaprine

    go.drugbank.com/drugs/DB00924
    ApprovedInvestigational

    Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977. … [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.

    Mixtures: DOBRIX ®, Therabenzaprine-90-5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Collagenase clostridium histolyticum

    go.drugbank.com/drugs/DB00048
    ApprovedInvestigational

    [L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum.

    Synonyms: Clostridiopeptidase A
  10. Drug

    IFx-Hu2.0

    go.drugbank.com/drugs/DB18396
    Investigational

    IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.

    Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linear