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Oxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A260396] Like most platinum-based compounds, oxaliplatin's mechanism of action is primarily through DNA damage through DNA crosslinking, particularly intrastrand and interstrand crosslinking. … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.
Categories: OCT2 Substrates with a Narrow Therapeutic IndexProducts: OXALIPLATINO SUN PHARMACEUTICAL INDUSTRIES EUROPE, OXALIPLATINO MYLAN GENERICSCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalCabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … [A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: CABAZITAXEL DR. REDDYSTerlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigationalTerlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … [A252672] The drug was first approved by the FDA in September 2022.[L43217]
Products: TERLIPRESSINA DR. REDDY'SPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigational[A187376] Phenylephrine was granted FDA approval in 1939.[L9413]
Mixtures: Select Brand Hemorrhoid, Select Brand Mucus Relief PECategories: Monoamine Oxidase A Substrates, Compounds used in a research, industrial, or household settingAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigationalAcemetacin is a carboxymethyl ester of indometacin. … [A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E.
Products: RANTUDIL ® LP 90 MG CAPSULAS DE LIBERACIÓN PROLONGADABaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalBaclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.
Synonyms: DL-Baclofen, DL-4-Amino-3-p-chlorophenylbutanoic acidProducts: Ozobax DS, BACLENO® 10MG/5ML SOLUCIÓN DE PERFUSIÓNFluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Synonyms: Furoate de fluticasone, Furoato de fluticasonaProducts: FUROATO DE FLUTICASONA 27.5 µG / 50 MCL, AVAMYS 2ADimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigational[L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide … [A253917] Prior to its FDA approval, dimethyl fumarate had been used in Germany for treatment of psoriasis.[A253917]
Products: D-FUMARIC 240 CAPSULAS DE LIBERACIÓN RETARDADA 240 MG, D-FUMARIC 120 CAPSULAS DE LIBERACION RETARDADA 120 MGHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalInfection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines.
Products: Hyperhep B S/d, HyperHEP B S/D INJECTIONTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]
Products: TORASEMIDE MYLAN GENERICS, SUTRILNEO 5 MG COMPRIMIDOS DE LIBERACIÓN PROLONGADA