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Displaying results 271 - 280 of 10000 in total
  1. Drug

    Camptothecin

    go.drugbank.com/drugs/DB04690
    Investigational

    Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, <i>Camptotheca acuminata</i>. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I.

    Synonyms: 20(S)-camptothecine, (S)-(+)-camptothecinCategories: P-glycoprotein substrates, Topoisomerase I Inhibitors
  2. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    It is currently marketed under the trademark TEMODAR® by Merck.[L32033] … [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: (S)-perillyl alcohol temozolomide, 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
  3. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine. … It is currently available in both tablet and nasal spray forms.[L12978]

    Synonyms: (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one, 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  4. Drug

    Hexanoyl-CoA

    go.drugbank.com/drugs/DB02563
    Experimental

    Synonyms: S-Hexanoyl-coenzym-A, S-hexanoyl-coenzyme-ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  5. Drug

    Bakuchiol

    go.drugbank.com/drugs/DB16102
    Investigational

    Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of Bakuchiol and Retinol).

    Synonyms: (s)-bakuchiol, Sytenol a
  6. Drug

    (+)-Mefloquine

    go.drugbank.com/drugs/DB05636
    Investigational

    in clinical trial NCT00931697 (Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine) to compare the efficacy of (+) Mefloquine vs

    Synonyms: (+)-(11R,2'S)-erythro-mefloquine, [(11R,2'S)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol
  7. Drug

    1,3,5-trichlorobenzene

    go.drugbank.com/drugs/DB03836
    Experimental

    Synonyms: s-trichlorobenzene
  8. Drug

    Amanozine

    go.drugbank.com/drugs/DB21366
    Experimental

    Amanozine is a small molecule drug. Amanozine has a monoisotopic molecular weight of 187.09 Da.

    Synonyms: 2-amino-4-anilino-s-triazine
  9. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained. … It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co.

    Synonyms: (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acidMixtures: PRAVAFEN® CAPSULAS
  10. Drug

    L-gamma-glutamyl-S-(naphthalen-1-ylmethyl)-L-cysteinylglycine

    go.drugbank.com/drugs/DB03885
    Experimental

    Synonyms: L-gammaGlu-S-(1-Naphthylmethyl)-L-Cys-Gly-OH, L-gamma-glutamyl-S-(naphthalen-1-ylmethyl)-L-cysteinylglycine