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Displaying results 271 - 280 of 10000 in total
  1. Drug

    METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE

    go.drugbank.com/drugs/DB07957
    Experimental

    Synonyms: METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
  2. Drug

    Carbinoxamine

    go.drugbank.com/drugs/DB00748
    Approved

    unapproved carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 … Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites.

    Mixtures: PHILDEX 2Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Procaine

    go.drugbank.com/drugs/DB00721
    ApprovedInvestigationalVet approved

    A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.

    Synonyms: 2-Diethylaminoethyl p-aminobenzoate, 4-aminobenzoic acid 2-diethylaminoethyl esterProducts: Novocain 20 mg/ml, NTCAIN 50 MG/5 ML IM AMPUL , 10 ADET
  4. Drug

    Sufentanil

    go.drugbank.com/drugs/DB00708
    ApprovedInvestigational

    (AcelRx), was approved on November 2, 2018 [L4717]. … Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide
  5. Drug

    Thiabendazole

    go.drugbank.com/drugs/DB00730
    ApprovedVet approvedWithdrawn

    2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 2-(thiazol-4-yl)benzimidazole, 4-(2-benzimidazolyl)thiazole
  6. Drug

    Dexlansoprazole

    go.drugbank.com/drugs/DB05351
    Approved

    Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and S-enantiomers. … [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production by blocking the (H+, K+)-ATPase enzyme.[L48827]

    Mixtures: DEXGARD 30/30 MG MR KAPSUL, 60 ADET, DEXGARD 30/30 MG MR KAPSUL, 30 ADETCategories: 2-Pyridinylmethylsulfinylbenzimidazoles, Heterocyclic Compounds, 2-Ring
  7. Drug

    Diethylamino hydroxybenzoyl hexyl benzoate

    go.drugbank.com/drugs/DB11269
    Approved

    Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. … It has a chemical structure similar to the classical benxophoenone drug class, and displays good photostability [A33171].

    Mixtures: Wonder Intensive BBCream 21 (Light), Age 20s ESSENCE COVER PACT WHITE DEEP BE-25Synonyms: Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate
  8. Drug

    Laurocapram

    go.drugbank.com/drugs/DB17308
    Approved

    Synonyms: 1-dodecylhexahydro-2h-azepin-2-one, 1-dodecylazacycloheptan-2-oneCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. … It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid
  10. Drug

    Cefotiam

    go.drugbank.com/drugs/DB00229
    Approved

    One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid