Cefotiam

DB00229ApprovedSmall molecule

Cefotiam is a cephalosporin antibiotic used to treat a variety of bacterial infections. One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

Chemical structure of Cefotiam
Mechanism
Curator reviewed
Primary indication
For treatment of severe infections caused by susceptible bacteria.Curator reviewed · 1 structured indication
Formula / weight
C18H23N9O4S3 · 525.628 g/mol (avg)

Resolves to

Compound
UNII91W6Z2N718CAS61622-34-2ChEMBLCHEMBL1296ChEBI355510PubChem43708KEGGD07648
Clinical / RWD
RxNorm2188ATCJ01DC07PharmGKBPA164749298
Structure
InChIKeyQYQDKDWGWDOFFU-IUODEOHRSA-NSMILES[H][C@]12SCC(CSC3=NN=NN3CCN(C)C)=C(N1C(=O)[C@H]2NC(=O)CC1=CSC(N)=N1)C(O)=O
Targets
Q8XJ01pbpAP0AD68ftsI
Transporters
Q4U2R8SLC22A6Q8TCC7SLC22A8

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2TransportersSubstrate / inhibitor direction, not just membership
Listed above
889Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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6Marketed productsAcross 1 country and 3 labellers
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1ATC codeIncluding every combination product, plus 17 drug categories
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10+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Cefotiam, and which of those have an active Phase 3 trial?

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