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Elzasonan
go.drugbank.com/drugs/DB18969InvestigationalElzasonan is under investigation in clinical trial NCT00275197 (A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive
Levotofisopam
go.drugbank.com/drugs/DB19073InvestigationalLevotofisopam is under investigation in clinical trial NCT01519687 (Study of Levotofisopam 50 Mg Three Times a Day (TID) Administered for 7 Days on Hyperuricemia and Gout).
Carfentanil
go.drugbank.com/drugs/DB01535IllicitInvestigationalVet approvedCurrently sufentanil, approximately 10–20 times less potent (500 to 1000 times the efficacy of morphine per weight) than carfentanil, is the maximum strength fentanyl analog for use in humans. … It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 microgram.
Ankyrin repeat and protein kinase domain-containing protein 1
go.drugbank.com/bio_entities/BE0009411TargetHumansPolypeptides: Ankyrin repeat and protein kinase domain-containing protein 1AZD0947
go.drugbank.com/drugs/DB04848ExperimentalAs of March 2003, the drug was in phase II trials; however, as of October 2004, it no longer appeared on the company’s development pipeline.
Cobomarsen
go.drugbank.com/drugs/DB14931InvestigationalCobomarsen is under investigation in clinical trial NCT02580552 (Safety, Tolerability and Pharmacokinetics of MRG-106 in Patients With Mycosis Fungoides (MF), CLL, DLBCL or ATLL).
Dinutuximab
go.drugbank.com/drugs/DB09077ApprovedInvestigationalIt is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk … restricted expression on normal tissues.
Fenfluramine
go.drugbank.com/drugs/DB00574ApprovedIllicitInvestigationalWithdrawn[A214688, A214691, A214700] Fenfluramine was granted initial FDA approval in 1973 prior to its withdrawal; it was granted a new FDA approval on June 25, 2020, for treatment of patients with Dravet syndrome … from the market in 1997.
Synonyms: 1-(m-trifluoromethyl-phenyl)-2-ethylaminopropaneLErafAON
go.drugbank.com/drugs/DB04973InvestigationalPhase I/II trials commenced in March 2001 and were ongoing as of June 2003.
Triheptanoin
go.drugbank.com/drugs/DB11677ApprovedInvestigational[A214817] Triheptanoin was granted FDA approval on 30 June 2020.[L14612] … [A214812,A214817] Complications in lc-FAOD patients are reduced from approximately 60% to approximately 10% with the addition of triheptanoin.