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Diphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalWhen diphenoxylate is used alone, it is classified as a Schedule II. … A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine.
Synonyms: Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate, 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl esterMixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML, LAMDOTIL®Tenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigational[L8558] It was first designed and synthesized in 2012. … [A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and therefore exists as
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: XPHOZAH 10 mg, XPHOZAH 20 mgSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigational[L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296] … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.
Mixtures: BACTAMED 500 MG/250 MG IM IV ENJEKTABL TOZ IÇEREN FLAKON, 10 ADET, PROBICID IV/IM 250 MG FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-RingMirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigationalIt inhibits the actions of interleukin-23 (IL-23), a pro-inflammatory cytokine that activates pathways contributing to the development of inflammatory diseases. … [L46252] It was officially approved in the EU in May 2023[L48656] and Canada in July 2023[L48661], and was eventually approved in the US in October 2023[L48651] for the treatment of adult patients with
Categories: Interleukin-23 AntagonistProducts: Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 2 ADET, Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 6 ADETOrismilast
go.drugbank.com/drugs/DB19042InvestigationalOrismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).
Synonyms: 2-(3,5-dichloro-1-oxido-4-pyridinyl)-1-(7-(difluoromethoxy)-2',3',5',6'-tetrahydro-1',1'-dioxidospiro(1,3-benzodioxole-2,4'-(4h)thiopyran)-4-yl)ethanoneMetacavir
go.drugbank.com/drugs/DB19084InvestigationalMetacavir is under investigation in clinical trial NCT02965859 (The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B).
Categories: Heterocyclic Compounds, 2-RingSynonyms: ((2s,5r)-5-(2-amino-6-methoxy-purin-9-yl)tetrahydrofuran-2-yl)methanol, 2',3'-dideoxy-6-o-methylguanosineGandotinib
go.drugbank.com/drugs/DB13040InvestigationalGandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Synonyms: 3-(4-CHLORO-2-FLUOROBENZYL)-2-METHYL-N-(5-METHYL-1H-PYRAZOL-3-YL)-8- (MORPHOLINOMETHYL)IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, 3-((4-CHLORO-2-FLUOROPHENYL)METHYL)-2-METHYL-N-(5- METHYL-1H-PYRAZOL-3-YL)-8-(4-MORPHOLINYLMETHYL)-Categories: Heterocyclic Compounds, 1-Ring, Janus Kinase 2, antagonists & inhibitorsLartesertib
go.drugbank.com/drugs/DB19045InvestigationalLartesertib is under investigation in clinical trial NCT06433219 (Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (Ddriver EOC 302)).
Synonyms: 2H-Imidazo[4,5-c]quinolin-2-one, 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-, (1S)-, 8-(1,3-dimethyl-1h-pyrazol-4-yl)-1-(3-fluoro-5-methoxy-4-pyridinyl)-1,3-dihydro-7-methoxy-3-methyl-2h-imidazo(4,5-c)quinolin-2-onePeginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalWhen combined together, Peginterferon alfa-2b and [Ribavirin] have been shown to achieve a SVR between 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment. … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by binding to human type 1 interferon receptors.
Categories: peginterferon alfa-2b, peginterferon alfa-2b, combinationsSynonyms: PEG-IFN-α-2b, Pegylated Interferon α-2bMometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMECUTAN SALBE 1 MG/G, MOMENSA (50 ตg/ACTUATION NASAL SPRAY , SUSPENSION)