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Displaying results 2851 - 2860 of 10000 in total
  1. Drug

    Pumosetrag

    go.drugbank.com/drugs/DB12402
    Investigational

    Pumosetrag has been used in trials studying Gastroesophageal Reflux Disease.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Mizoribine

    go.drugbank.com/drugs/DB12617
    Investigational

    Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.

  3. Drug

    Patidegib

    go.drugbank.com/drugs/DB12655
    Investigational

    Patidegib has been investigated for the treatment of Conventional Chondrosarcoma.

  4. Drug

    BMS-582949

    go.drugbank.com/drugs/DB12696
    Investigational

    BMS-582949 has been investigated for the treatment of Psoriasis.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    BMS-488043

    go.drugbank.com/drugs/DB05532
    Experimental

    BMS-488043 has been investigated as an anti-HIV agent.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    PH-797804

    go.drugbank.com/drugs/DB07941
    Investigational

    PH-797804 has been investigated for the treatment of Osteoarthritis.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Tivozanib

    go.drugbank.com/drugs/DB11800
    ApprovedInvestigational

    Marketed by Aveo Oncology, tivozanib is a promising therapy for individuals with RCC who have not been treated successfully with other therapies.[L32524] … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  8. Drug

    Lotilaner

    go.drugbank.com/drugs/DB17992
    ApprovedInvestigationalVet approved

    [L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals. … [A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active _in vivo_, while the R-enantiomer is reported to exhibit low biological activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide
  9. Drug

    Potassium nitrate

    go.drugbank.com/drugs/DB11090
    ApprovedInvestigational

    It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. … Potassium nitrate is an inorganic salt with a chemical formula of KNO3.

    Mixtures: Ionite H, Ionite HCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Oxymetholone

    go.drugbank.com/drugs/DB06412
    ApprovedIllicit

    Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes. … The uncontrolled misuse of oxymetholone can lead to a large variety of detrimental effects, the most often reported of which are cardiovascular events.

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: 17β-Hydroxy-2-hydroxymethylidene-17α-methyl-3-androstanone