Mizoribine

DB12617InvestigationalSmall molecule

Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.

Mechanism: Pharmacologically active on GMP synthase [glutamine-hydrolyzing] and Inosine-5'-monophosphate dehydrogenase
Curator reviewed
Formula / weight: C₉H₁₃N₃O₆ · 259.216 g/mol (avg)
Also known as: BREDININ

Resolves to

Compound

Structure

InChIKeyHZQDCMWJEBCWBR-UUOKFMHZSA-NSMILESNC(=O)C1=C(O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Targets

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

434Drug interactionsStructured to mechanism, not free text

6Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Mizoribine, and which of those have an active Phase 3 trial?

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