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Saxagliptin
go.drugbank.com/drugs/DB06335ApprovedInvestigationalSaxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Synonyms: (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrileMixtures: Qtern 5 mg/10 mg Film-Coated Tablets, QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADETOpium
go.drugbank.com/drugs/DB11130ApprovedIllicitIt has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. … During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive.[A32171] Opium is extracted from _Papaver somniferum_, which is more known as poppies.
Mixtures: Donnagel-PG Liq, Donnagel-PG CapCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesIodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalAs a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, while the other 90% (beta radiation) causes tissue damage without contributing to any ability to see … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy.
Synonyms: 131 I, 131-ISalts: Sodium iodide I-131Estradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approved[DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%). … The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle.
Mixtures: DIVICONT TABLETAS 1 MG/5 MG, MESIGYNA 5 MG+50 MG/1 ML ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTÖRCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approved(From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.
Mixtures: Lactic Acid 10% / Niacinamide 4%, Selutrio 10Synonyms: 2-Hydroxypropanoic acid, 2-Hydroxypropionic acidSunobinop
go.drugbank.com/drugs/DB18955InvestigationalSunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation).
Synonyms: 4-((1r,1'r,3r,3'r,5s,5's)-9'-aza(3,9'- bi(bicyclo(3.3.1)nonan))-3'-yl)-3-oxo-3,4- dihydroquinoxaline-2-carboxylic acid, 2-quinoxalinecarboxylic acid, 4-((3-endo)-9-(3-exo)-bicyclo(3.3.1)non-3-yl-9-azabicyclo(3.3.1)non-3-yl)-3,4-dihydro-3-oxo-Cilazapril
go.drugbank.com/drugs/DB01340ApprovedInvestigationalIt belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these varieties are available in the United States.
Mixtures: ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADET, Inhibace plus 5 mg/12,5 mg - FilmtablettenCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigational[L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602] … Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961.
Categories: Experimental Unapproved Treatments for COVID-19, P-glycoprotein inducersProducts: Colctab 1 mg Tabletten, Colchanova 1 mg TablettenNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33714,L33719] Naloxone was granted FDA approval on 13 April 1971.[L33709] … Notably, if injected into a person not currently using opioid medications, there would be no noticeable effects at all.
Synonyms: 1-N-Allyl-14-hydroxynordihydromorphinone, 17-allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-oneMixtures: Targin 10 mg/5 mg Retardtabletten, Oxylanox 10 mg/5 mg-RetardtablettenBetaxolol
go.drugbank.com/drugs/DB00195ApprovedInvestigationalA cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Categories: Adrenergic beta-1 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol, 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol