Search

Displaying results 2861 - 2870 of 10000 in total
  1. Target

    tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

    go.drugbank.com/bio_entities/BE0020091
    EnzymeHumans

    Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565). Specifically modifies U20 in cytoplasmic ...

    Polypeptides: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
  2. Drug

    Relmapirazin

    go.drugbank.com/drugs/DB19130
    Investigational

    Relmapirazin is under investigation in clinical trial NCT05425719 (Pharmacokinetics and Safety of MB-102 (Relmapirazin) and the Medibeacon Transdermal GFR Measurement System in Evaluation of Kidney Function

  3. Drug

    Collagenase clostridium histolyticum

    go.drugbank.com/drugs/DB00048
    ApprovedInvestigational

    [L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease.

  4. Drug

    NKG2D-ACE2 CAR-NK Cell

    go.drugbank.com/drugs/DB15727
    Investigational

    The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity. … These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF.

  5. Drug

    MK-8189

    go.drugbank.com/drugs/DB19153
    Investigational

    MK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).

  6. Drug

    Brilliant green cation

    go.drugbank.com/drugs/DB11279
    ApprovedVet approved

    Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.

    Mixtures: Kerr 100 Triple Dye Dispos-A
  7. Drug

    Vepdegestrant

    go.drugbank.com/drugs/DB19006
    ApprovedInvestigational

    [L56181] It is indicated for the treatment of adults with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, and ESR1-mutated advanced or metastatic breast cancer … Vepdegestrant is a potent, selective, and orally bioavailable PROteolysis TArgeting Chimera (PROTAC) small molecule estrogen receptor (ER) degrader.

  8. Drug

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid

    go.drugbank.com/drugs/DB16029
    Investigational

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).

  9. Drug

    Velusetrag

    go.drugbank.com/drugs/DB12702
    Investigational

    It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance.

  10. Drug

    alpha-Linolenic acid

    go.drugbank.com/drugs/DB00132
    ApprovedInvestigationalNutraceuticalWithdrawn

    It is a component of many common vegetable oils and is important to human nutrition.

    Mixtures: SIMILAC ALIMENTUM 400 G TOZ, PRIM E CAPSULE