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Displaying results 2861 - 2870 of 10000 in total
  1. Drug

    Elacestrant

    go.drugbank.com/drugs/DB06374
    ApprovedInvestigational

    [L44918,L44948] It received a similar approval in the EU in September 2023. … [A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.

  2. Drug

    MK-2748

    go.drugbank.com/drugs/DB15371
    Investigational

    MK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)).

  3. Drug

    Amrubicin

    go.drugbank.com/drugs/DB06263
    Investigational

    Pharmion licensed the rights to Amrubicin in November 2006. In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both SCLC and NSCLC. … Since January 2005, Amrubicin has been marketed by Nippon Kayaku, a Japanese pharmaceutical firm focused on oncology, which licensed Japanese marketing rights from Dainippon Sumitomo, the original developer

  4. Drug

    Tangerine peel

    go.drugbank.com/drugs/DB14316
    Investigational

    It is not an approved drug.

    Synonyms: Chen Pi
  5. Drug

    Vepdegestrant

    go.drugbank.com/drugs/DB19006
    ApprovedInvestigational

    [L56181] It is indicated for the treatment of adults with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, and ESR1-mutated advanced or metastatic breast cancer … Vepdegestrant is a potent, selective, and orally bioavailable PROteolysis TArgeting Chimera (PROTAC) small molecule estrogen receptor (ER) degrader.

  6. Drug

    rhMBL

    go.drugbank.com/drugs/DB05237
    Investigational

    Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide chains. … MBL forms different oligomers but must form at least a tetramer to be active.

  7. Drug

    Fluoride ion

    go.drugbank.com/drugs/DB11257
    ApprovedInvestigational

    It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. … It also plays an essential physiological role, such as enhancing the resistance profile and strength of the surface tooth enamel.

    Mixtures: ZYMAFLUOR D 1000, ZYMAFLUOR D 500
  8. Drug

    Magnesium orotate

    go.drugbank.com/drugs/DB13786
    Experimental

    It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. … It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers.

  9. Drug

    Melphalan flufenamide

    go.drugbank.com/drugs/DB16627
    ApprovedWithdrawn

    [A230123] _In vitro_ models show that melphalan is 10 to hundreds of times more potent than melphalan. … [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed or refractory multiple myeloma who have attempted at least 4 lines of therapy already.

  10. Drug

    Rhubarb

    go.drugbank.com/drugs/DB10651
    Approved

    Rhubarb allergenic extract is used in allergenic testing.

    Mixtures: ORALDIN ÇÖZELTI ,10 ML-1 ŞIŞE, PIRALDYNE ORAL SOLUSYON 10 ML