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Displaying results 2871 - 2880 of 10000 in total
  1. Drug

    CB-103

    go.drugbank.com/drugs/DB15279
    Investigational

    CB-103 is under investigation in clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies).

    Synonyms: 3-PYRIDINAMINE, 6-(4-(1,1-DIMETHYLETHYL)PHENOXY)-, 6-(4-(1,1-Dimethylethyl)phenoxy)-3-pyridinamine
  2. Drug

    Tebentafusp

    go.drugbank.com/drugs/DB15283
    ApprovedInvestigational

    Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. … [L39995] It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a novel mechanism

    Categories: Bispecific gp100 Peptide-HLA-directed CD3 T Cell Engager
  3. Drug

    ARC-19499

    go.drugbank.com/drugs/DB15285
    Investigational

    ARC-19499 is under investigation in clinical trial NCT01191372 (First-in-Human and Proof-of-Mechanism Study of ARC19499 Administered to Hemophilia Patients).

  4. Drug

    Etamicastat

    go.drugbank.com/drugs/DB15288
    Investigational

    Etamicastat is under investigation in clinical trial NCT02840565 (Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  5. Drug

    Hydroquinidine

    go.drugbank.com/drugs/DB15300
    Investigational

    Hydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).

    Categories: Antiarrhythmics, Class I, Heterocyclic Compounds, 2-Ring
  6. Drug

    Bevifimod

    go.drugbank.com/drugs/DB15301
    Investigational

    Bevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis).

    Synonyms: STAPHYLOCOCCAL PROTEIN A
  7. Drug

    2-fluorofucose

    go.drugbank.com/drugs/DB15302
    Investigational

    2-fluorofucose is under investigation in clinical trial NCT02952989 (A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors).

    Synonyms: 2-fluorofucose
  8. Drug

    Risdiplam

    go.drugbank.com/drugs/DB15305
    ApprovedInvestigational

    This mechanism of action is similar to its predecessor [nusinersen], the biggest difference being their route of administration: nusinersen requires intrathecal administration, as does the one-time gene … Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA).

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  9. Drug

    Atabecestat

    go.drugbank.com/drugs/DB15307
    Investigational

    Atabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9,

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Hypothiocyanite ion

    go.drugbank.com/drugs/DB15309
    Investigational

    Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients).