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Displaying results 2871 - 2880 of 5451 in total
  1. Drug

    Pimethixene

    go.drugbank.com/drugs/DB13292
    Approved

    It is an anticholinergic used in the treatment of bronchitis.

  2. Drug

    Etilefrine

    go.drugbank.com/drugs/DB08985
    ApprovedWithdrawn

    It has been used as a vasoconstrictor agent.

    International brands: Eti-PurenProducts: Effortil 7,5 mg/ml - Tropfen, ETILEFRINACLORHIDRATO 10 MG /ML
  3. Drug

    Pipamperone

    go.drugbank.com/drugs/DB09286
    Investigational

    Interestingly, when [risperidone] was created, Janssen suggested it was a more potent version of pipamperone. … It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518].

  4. Drug

    Dronedarone

    go.drugbank.com/drugs/DB04855
    ApprovedInvestigational

    It is managed by rate control, rhythm control, prevention of thromboembolic events, and treatment of the underlying disease. … [A186071] It meets criteria of all four Vaughan Williams antiarrhythmic drug classes by blocking sodium, potassium, and calcium ion channels and inhibiting β-adrenergic receptors.

    Products: MULTAQ (400 MG), MULTAQ 400 MG FILM-COATED TABLETS
  5. Drug

    Mibefradil

    go.drugbank.com/drugs/DB01388
    ApprovedWithdrawn

    Mibefradil was withdrawn from the market in 1998 because of potentially harmful interactions with other drugs.

  6. Drug

    Laronidase

    go.drugbank.com/drugs/DB00090
    ApprovedInvestigational

    It contains 6 N-linked oligosaccharide modification sites. … The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase.

  7. Drug

    Alitretinoin

    go.drugbank.com/drugs/DB00523
    Approved

    It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute).

    Products: Alitretan 10 mg Kapseln, Alitretan 30 mg Kapseln
  8. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    It is produced in vivo from androstenedione or from testosterone via estradiol. … It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.

    Products: Oestrilin Creme Vaginale 1mg
  9. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    [L32113] It first received FDA approval on April 27, 2012,[L32058] with subsequent EMA approval in June 2013.[L32113] … In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively

    Products: STENDRA 100 MG TABLET, 2 ADET, STENDRA 100 MG TABLET, 4 ADET
  10. Drug

    Sodium stibogluconate

    go.drugbank.com/drugs/DB05630
    ApprovedInvestigational

    It is also being investigated as an anti-tumor agent. … It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline).