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Cevimeline
go.drugbank.com/drugs/DB00185ApprovedIt is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Categories: Cholinergic Receptor AgonistCaroxazone
go.drugbank.com/drugs/DB09254ApprovedWithdrawnHowever, it presents a five-fold preference for the MAO-B subtype.
Vapreotide
go.drugbank.com/drugs/DB04894InvestigationalIt was being studied for the treatment of cancer.
Carbocromen
go.drugbank.com/drugs/DB13279ApprovedWithdrawnCarbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development [L5635].
Glafenine
go.drugbank.com/drugs/DB08963ApprovedWithdrawnAn anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
Berdazimer
go.drugbank.com/drugs/DB18712Approved[A262965] On Jan 05, 2024, the FDA approved berdazimer under the brand name ZELSUVMI for the treatment of adult and pediatric molluscum contagiosum, and it is the first drug to be approved for this … [A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and immunocompromised
Pizotifen
go.drugbank.com/drugs/DB06153Approved[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin Receptor AntagonistsKetobemidone
go.drugbank.com/drugs/DB06738InvestigationalThis makes it useful for some types of pain that don't respond well to other opioids. … The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.
Hydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalHydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the...
Pyridoxal phosphate
go.drugbank.com/drugs/DB00114ApprovedInvestigationalNutraceuticalThis is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.