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Displaying results 2881 - 2890 of 10000 in total
  1. Drug

    Angelica sinensis root

    go.drugbank.com/drugs/DB14336
    Investigational

    Angelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: Dang Gui Tou, Dang Gui Wei
  2. Drug

    Osimertinib

    go.drugbank.com/drugs/DB09330
    ApprovedInvestigational

    [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations are correlated with response to therapy. … testing and which has progressed following therapy with a first-generation EGFR tyrosine kinase inhibitor.

    Synonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamideCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic Index
  3. Drug

    Zolpidem

    go.drugbank.com/drugs/DB00425
    ApprovedInvestigational

    Research also shows that zolpidem is rapid and effective in restoring brain function for patients in a vegetative state following brain injury. … Zolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia.

    Mixtures: Gabazolpidem-5, Sentrazolpidem PM-5Categories: GABA-A Receptor Agonists, Cytochrome P-450 Substrates
  4. Drug

    Sevelamer

    go.drugbank.com/drugs/DB00658
    ApprovedInvestigational

    Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.

    Categories: Compounds used in a research, industrial, or household settingProducts: <html>RENALAMER CO<sub>3</sub> 800 MG FILM TABLET, 180 ADET</html>, RENVELA 2,4 G ORAL SÜSPANSIYON IÇIN TOZ, 60 SAŞE
  5. Drug

    Artesunate

    go.drugbank.com/drugs/DB09274
    ApprovedInvestigational

    [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin].[A203948] Artesunate was granted FDA approval on 26 May 2020.[L14099]

    Mixtures: อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 25/55 มก.Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  6. Drug

    Alanyl glutamine

    go.drugbank.com/drugs/DB11876
    Investigational

    Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).

    Synonyms: N(2)-L-Alanyl-L-glutamine, L-Alanyl-L-glutamineProducts: GLUTAVIVEN 20 G/100 ML IV INF. ICIN KONSANTRE COZELTI İÇEREN FLAKON, DİPEPİTVEN %20 İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ, 100 ML
  7. Drug

    Sorafenib

    go.drugbank.com/drugs/DB00398
    ApprovedInvestigational

    Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. … [A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also indicated to treat renal carcinoma and differentiated thyroid carcinoma

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea, 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide
  8. Drug

    Carglumic acid

    go.drugbank.com/drugs/DB06775
    ApprovedInvestigational

    Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. … Food and Drug Administration (FDA) on 18 March 2010.

    Synonyms: (2S)-2-(carbamoylamino)pentanedioic acid, (S)-2-ureidopentanedioic acidCategories: Carbamoyl Phosphate Synthetase 1 Activator, Carbamoyl Phosphate Synthetase 1 Activators
  9. Drug

    Benzyl alcohol

    go.drugbank.com/drugs/DB06770
    ApprovedInvestigational

    Mixtures: ZOLBENE CREMA TOPICA (CALAMINA 5% + OXIDO DE ZINC 5% + ALCOHOL BENCILICO 1%), Fast Freeze Lidocaine Roll-OnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  10. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. … [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.

    Mixtures: UR N-C Urinary Antiseptic, Me NaPhos MB Hyo 1Synonyms: [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (S)-atropine