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Marnetegragene autotemcel
go.drugbank.com/drugs/DB17595Approved[L56116, A275467] Allogeneic hematopoietic stem cell transplant is a curative option but is limited by issues such as donor availability, a high incidence of graft-versus-host disease, and graft failure … Severe leukocyte adhesion deficiency-I (LAD-I) is a genetic disorder leading to frequent life-threatening infections and high fatality risks among affected pediatric patients.
Synonyms: Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene, Autologous CD34+ cells transduced ex vivo with a lentiviral vector (Chim-CD18-WPRE) encoding the ITGB2 geneMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingRecombinant human arylsulfatase A
go.drugbank.com/drugs/DB17671InvestigationalSynonyms: Recombinant human arylsulfatase A, Recombinant human arylsulphatase AAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigationalAlprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. … [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death.
Mixtures: Sentrazolam AM, NEUPAX DUO-SCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingA-dmDT390-bisFv(UCHT1)
go.drugbank.com/drugs/DB16307InvestigationalA-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides).
Synonyms: Anti-cd3 immunotoxin a-dmdt390-bisfv(ucht1)6-methyl-formycin A
go.drugbank.com/drugs/DB03986ExperimentalSynonyms: 6-methyl-formycin A, 2-(7-amino-6-methyl-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diolDordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigationalDordaviprone is a first-in-class small molecule imipridone. On August 6, 2025, dordaviprone was granted accelerated approval by the FDA. … [L53833] Dordaviprone was initially studied as an anticancer agent that induces TNF-Related Apoptosis-Inducing Ligand (TRAIL).
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one, 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-onePentetic acid
go.drugbank.com/drugs/DB14007ApprovedInvestigational[A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ingredients for drug products by the FDA. … Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable
Categories: Compounds used in a research, industrial, or household settingSynonyms: DTP-AMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalMirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy.
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-AzamianserinCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor Antagonists