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Vardenafil
go.drugbank.com/drugs/DB00862Approvedof cGMP in the smooth muscle cells of the corpus cavernosum. … [A258318] The FDA approved the use of vardenafil for the treatment of erectile dysfunction in 2003.
Categories: Drugs Used in Erectile DysfunctionRauwolfia serpentina root
go.drugbank.com/drugs/DB09363InvestigationalMultiple studies have been done on their biosynthetic potential and numerous biotechnological methods used to study the production of pharmaceutically important alkaloids [A32095, A32096]. … Rauwolfia (Rauwolfia serpentina), also spelled _ravolphia_, is a medicinal plant in the milkweed family. The root of the plant is ground into a powder or sold in tablets or capsules.
Categories: combinations of rauwolfia alkaloidsRimantadine
go.drugbank.com/drugs/DB00478ApprovedAn RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Dorocubicel
go.drugbank.com/drugs/DB19448Approved[L54146] It is one component of a cell therapy, Zemcelpro, that also contains [unexpanded umbilical cord-derived allogeneic CD34- hematopoietic stem cells]. … [L54106] Dorocubicel, as a component of Zemcelpro, was granted conditional marketing authorization in the European Union in August 2025 for use in allogeneic hematopoietic stem cell transplantation
MVC-COV1901
go.drugbank.com/drugs/DB15854InvestigationalThe vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. … As of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity (NCT04487210).
Zopapogene imadenovec
go.drugbank.com/drugs/DB24672ApprovedInvestigationalFood and Drug Administration (FDA) for the treatment of adults with RRP, receiving full FDA approval on August 15, 2025.[L54081] … [L54081] Zopapogene imadenovec is a non-replicating adenoviral vector–based immunotherapy that expresses a fusion antigen from selected regions of HPV-6/11 proteins to elicit an immune response in RRP.
Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, Replication-deficient gorilla adenovirus vector (strain GC46) encoding human papillomavirus (HPV) type 6 and type 11 antigens comprising 11 epitopes derived from regions of the E2, E4, E6, and E7 proteinsTideglusib
go.drugbank.com/drugs/DB12129ApprovedInvestigationalWithdrawn[A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012. … It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3).
Armodafinil
go.drugbank.com/drugs/DB06413ApprovedInvestigationalapnea (OSA), narcolepsy, or shift work disorder (SWD). … Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil.
Categories: Metabolic Side Effects of Drugs and SubstancesRose bengal I-131
go.drugbank.com/drugs/DB09388ApprovedCategories: Compounds used in a research, industrial, or household settingOmapatrilat
go.drugbank.com/drugs/DB00886ExperimentalThe inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling. … This drug from BMS was not approved by the FDA due to angioedema safety concerns.
Categories: Agents Acting on the Renin-Angiotensin System