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Reldesemtiv
go.drugbank.com/drugs/DB15256InvestigationalReldesemtiv is under investigation in clinical trial NCT03160898 (A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)).
Arbaclofen Placarbil
go.drugbank.com/drugs/DB08892InvestigationalIt was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties.
Trimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalTrimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic respon...
Daclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnOn 22 April 2008, Roche Registration Limited chose to voluntarily withdraw the marketing authorization for their product Zenapax (daclizumab), as indicated for the prophylaxis of acute organ rejection … Regardless of the withdrawal of Zenapax, Biogen and Abbvie's Zinbryta (daclizumab), as indicated for the treatment of adult patients with relapsing forms of multiple sclerosis, was approved for use by
Glofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigationalmany as 40% of patients will experience relapsed or refractory disease. … ,A258433] In the context of relapsed or refractory DLBCL, glofitamab provides an alternative treatment option for patients having failed other systemic therapies or for whom targeted therapies - such as
Voxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalTreatment options for chronic Hepatitis C have advanced significantly since 2011, with the development of Direct Acting Antivirals (DAAs) such as voxilaprevir. … Voxilaprevir has been available since July 2017 in a fixed dose combination product with [sofosbuvir] and [velpatasvir] as the commercially available product Vosevi.
Palmidrol
go.drugbank.com/drugs/DB14043InvestigationalNutraceuticalPalmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets). … A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection.
Benzoctamine
go.drugbank.com/drugs/DB09021ExperimentalIt can also be used as an anxiolytic with the same efficacy as chlordiazepoxide for treating anxiety neurosis. … It can be used as a sedative which does not depress the respiratory system, but rather stimulates it.
Custirsen
go.drugbank.com/drugs/DB05487InvestigationalCustirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells.