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Dimethyl sulfone
go.drugbank.com/drugs/DB14090InvestigationalMixtures: Medison Bell Pill Patch, Medison Bell Pill PatchOrphenadrine
go.drugbank.com/drugs/DB01173ApprovedInvestigationalA muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsFerric cation
go.drugbank.com/drugs/DB13949ApprovedWithdrawnResulting from inadequate supply of iron to cells due to depletion of stores, iron deficiency is the most common nutritional deficiency worldwide, particularly affecting children, women of childbearing … Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and energy production in electron transport [A32514].
Aluminium
go.drugbank.com/drugs/DB01370ApprovedInvestigationalWithdrawnA metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
Zidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group.
Mixtures: ZOVILAM PED DT®Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesFosphenytoin
go.drugbank.com/drugs/DB01320ApprovedInvestigationalFosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use...
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesThenalidine
go.drugbank.com/drugs/DB04826ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Denufosol
go.drugbank.com/drugs/DB04983InvestigationalDenufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial.
Capmatinib
go.drugbank.com/drugs/DB11791ApprovedInvestigational[L13380] As this indication was granted under an accelerated approval, its continued approval is contingent upon verification of capmatinib's benefit in confirmatory trials. … [L13347] The presence of the mutation must be confirmed by an FDA-approved test, such as the FoundationOne CDx assay (manufactured by Foundation Medicine, Inc.), which was approved by the FDA on the same
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesMetrizamide
go.drugbank.com/drugs/DB01578ExperimentalMetrizamide is a solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity. It is also used as a resorbable, non-ionic contrast medium.