Dimethyl sulfone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Dimethyl sulfone
Accession Number
DB14090
Description
Not Available
Type
Small Molecule
Groups
Experimental, Investigational
Structure
Thumb
Weight
Average: 94.133
Monoisotopic: 94.008850126
Chemical Formula
C2H6O2S
Synonyms
  • Dimethyl sulphone
  • Methyl sulfone
  • Methylsulfonyl methane
  • Methylsulfonylmethane
  • MSM
  • Sulfonylbismethane

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Learn about our commercial Adverse Effects data.
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
MsmTablet0.51 g/0.51gOralInc MBG2019-01-24Not applicableUS flag
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
DOCTOR HOYS Arnica BoostDimethyl sulfone (2 g/1mL) + Arnica montana flower (5 g/1mL)CreamTopicalDoctor Hoy's, Llc2013-08-012019-07-18US flag
IMPLAHeal P.OCreamDimethyl sulfone (1 g/100mL) + N-Acetylglucosamine (2 g/100mL)CreamTopicalThreedayslove Co., Ltd.2019-12-16Not applicableUS flag
Powerfulx Ginseng RecoveryCreamDimethyl sulfone (0.1 g/100mL) + N-Acetylglucosamine (0.15 g/100mL) + Panax ginseng root oil (66.2186 g/100mL)CreamTopicalPowerful X2018-12-10Not applicableUS flag
TENHEALER Pain RubDimethyl sulfone (15 mg/1mL) + Levomenthol (50 mg/1mL) + Methyl salicylate (150 mg/1mL) + Synthetic camphor (50 mg/1mL)LotionTopicalBIO HEALING THERAPY INDUSTRIES INC2019-08-01Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
DOCTOR HOYS Arnica BoostDimethyl sulfone (2 g/1mL) + Arnica montana flower (5 g/1mL)CreamTopicalDoctor Hoy's, Llc2013-08-012019-07-18US flag
IMPLAHeal P.OCreamDimethyl sulfone (1 g/100mL) + N-Acetylglucosamine (2 g/100mL)CreamTopicalThreedayslove Co., Ltd.2019-12-16Not applicableUS flag
Medi-flexx Rx Joint Support FormulaDimethyl sulfone (200 mg/1) + Chondroitin sulfate (chicken) (400 mg/1) + Glucosamine sulfate (500 mg/1)TabletOralTwo Hip Consulting, Llc2014-12-052016-04-11US flag
MsmDimethyl sulfone (0.51 g/0.51g)TabletOralInc MBG2019-01-24Not applicableUS flag
Powerfulx Ginseng RecoveryCreamDimethyl sulfone (0.1 g/100mL) + N-Acetylglucosamine (0.15 g/100mL) + Panax ginseng root oil (66.2186 g/100mL)CreamTopicalPowerful X2018-12-10Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as sulfones. These are compounds containing a sulfonyl group( which as the general structure RS(=O)2R' (R,R' =alkyl, aryl)) attached to two carbon atoms.
Kingdom
Organic compounds
Super Class
Organosulfur compounds
Class
Sulfonyls
Sub Class
Sulfones
Direct Parent
Sulfones
Alternative Parents
Organic oxides / Hydrocarbon derivatives
Substituents
Aliphatic acyclic compound / Hydrocarbon derivative / Organic oxide / Organic oxygen compound / Sulfone
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
sulfone (CHEBI:9349) / a sulfone (CPD-10437)

Chemical Identifiers

UNII
9H4PO4Z4FT
CAS number
67-71-0
InChI Key
HHVIBTZHLRERCL-UHFFFAOYSA-N
InChI
InChI=1S/C2H6O2S/c1-5(2,3)4/h1-2H3
IUPAC Name
methanesulfonylmethane
SMILES
CS(C)(=O)=O

References

General References
Not Available
Human Metabolome Database
HMDB0004983
KEGG Compound
C11142
ChemSpider
5978
BindingDB
50026473
RxNav
23247
ChEBI
9349
ChEMBL
CHEMBL25028
ZINC
ZINC000004658606
Wikipedia
Methylsulfonylmethane

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3RecruitingTreatmentBack Pain Lower Back1
1Unknown StatusSupportive CareOsteoarthritis (OA)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
CapsuleOral
CreamTopical
Powder, for solutionOral2400 mg
Powder, for solutionOral1.2 g
TabletOral
TabletOral0.51 g/0.51g
Tablet, delayed releaseOral600 mg
Powder, for solutionOral1200 mg
LotionTopical
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility55.8 mg/mLALOGPS
logP-0.95ALOGPS
logP-1.3ChemAxon
logS-0.23ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area34.14 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity20.53 m3·mol-1ChemAxon
Polarizability8.6 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
MS/MS Spectrum - Quattro_QQQ 10V, PositiveLC-MS/MSsplash10-0002-9000000000-9896ec507f104ada81f3
MS/MS Spectrum - Quattro_QQQ 25V, PositiveLC-MS/MSsplash10-014i-9000000000-aad0ad2e46e9a93df295
MS/MS Spectrum - Quattro_QQQ 40V, PositiveLC-MS/MSsplash10-014i-9000000000-8cb5ee5ae152833c1e84
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available
1H NMR Spectrum1D NMRNot Applicable
[1H,13C] 2D NMR Spectrum2D NMRNot Applicable

Drug created on June 18, 2018 10:42 / Updated on June 12, 2020 10:53

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