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Displaying results 2901 - 2910 of 9132 in total
  1. Drug

    Mephenytoin

    go.drugbank.com/drugs/DB00532
    ApprovedWithdrawn

    Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. … Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures.

  2. Drug

    Ornithine

    go.drugbank.com/drugs/DB00129
    ApprovedInvestigationalNutraceutical

    L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine. … Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine.

  3. Drug

    Apc001

    go.drugbank.com/drugs/DB17819
    Experimental

    Apc001 is an aptamer developed for the treatment of osteogenesis imperfecta.

  4. Drug

    HLX-58

    go.drugbank.com/drugs/DB18699
    Experimental

    HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.

  5. Drug

    BA1301

    go.drugbank.com/drugs/DB19390
    Investigational

    BA1301 is an anti-Claudin18.2 monoclonal antibody conjugated with Duostatin-5.

  6. Drug

    Linagliptin

    go.drugbank.com/drugs/DB08882
    ApprovedInvestigational

    Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes [L9557]. … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050

  7. Drug

    ALTU-135

    go.drugbank.com/drugs/DB05330
    Investigational

    ALTU-135 has been granted orphan drug and fast-track designation as well as CMA Pilot 2 program status by the Food and Drug Administration (FDA).

  8. Drug

    Nitroxoline

    go.drugbank.com/drugs/DB01422
    Experimental

    It is a hydroxyquinoline derivative unrelated to other classes of drugs.[A179251] Nitroxoline is active against bacterial gyrases. … Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.

  9. Drug

    BBM-H803

    go.drugbank.com/drugs/DB17700
    Investigational

    It consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene. … BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed.

  10. Drug

    Hu-rhEGF-rP64k/Mont

    go.drugbank.com/drugs/DB15781
    Investigational

    Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated