DB01422ExperimentalSmall molecule
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a hydroxyquinoline derivative unrelated to other classes of drugs....
- Mechanism
- Curator reviewed
This drug may also have antitumor activity by inhibition of type 2 methionine aminopeptidase (MetAP2) protein which is involved in angiogenesis. Its antibacterial activity may stem from the metal ion complexation vital for bacterial growth.
- Primary indication
- Nitroxoline is an antibiotic agent.Curator reviewed
- Formula / weight
- C9H6N2O3 · 190.1555 g/mol (avg)
- Also known as
- 5-Nitrox · 5-NOK · 5NOK
- Code names
- A-82
Resolves to
Clinical / RWD
Structure
InChIKey
RJIWZDNTCBHXAL-UHFFFAOYSA-NSMILESOC1=C2N=CC=CC2=C(C=C1)[N+]([O-])=OTargets
What you can answer from here — as of September 12, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Nitroxoline, and which of those have an active Phase 3 trial?
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