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Dolasetron
go.drugbank.com/drugs/DB00757ApprovedInvestigationalDolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist. … This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingVolixibat
go.drugbank.com/drugs/DB13914InvestigationalVolixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane protein primarily expressed by enterocytes of the ileum. … Inhibiting this enzyme results in a decrease of bile acids returning to the liver, which is helpful for the treatment of NASH as abnormal cholesterol metabolism and accumulation of free cholesterol in
Categories: Heterocyclic Compounds, 2-RingRI 624
go.drugbank.com/drugs/DB05892ExperimentalRI 624 is being developed by Rinat and is currently in Phase I clinical trials. … RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain.
Ethanolamine oleate
go.drugbank.com/drugs/DB06689ApprovedEthanolamine oleate is a mild sclerosing agent. … It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.
Categories: Compounds used in a research, industrial, or household settingBifeprunox
go.drugbank.com/drugs/DB04888InvestigationalBifeprunox is a novel atypical antipsychotic agent which, along with SLV313, [aripiprazole] and SSR-181507 combines minimal D2 receptor agonism with 5-HT receptor agonism.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingCinitapride
go.drugbank.com/drugs/DB08810InvestigationalCinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.
Synonyms: 4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamideMixtures: ROGASTRIL PLUS®, ROGASTRIL PLUS®Glofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigationalThis approval is based on the positive results obtained from the phase I/II NP30179 study, where 35.2% of study participants achieved a complete response.[L47451] … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively.
Categories: Bispecific CD20-directed CD3 T Cell EngagerTianeptine
go.drugbank.com/drugs/DB09289InvestigationalTianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) [A31983]. … Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants [A31969].
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesIothalamic acid
go.drugbank.com/drugs/DB09133ApprovedIothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Synonyms: 1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamateSalts: Iothalamate sodium I-125Calcium glubionate anhydrous
go.drugbank.com/drugs/DB13142ApprovedCalcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Synonyms: (D-gluconato)(lactobionato)calcium, Calcium D-gluconate lactobionateProducts: CALCIUM SANDOZ %10 AMPUL, 5 ADET, CALCIUM SANDOZ 10 ML 1,375 GR AMPUL, 5 ADET