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Pegfilgrastim
go.drugbank.com/drugs/DB00019ApprovedInvestigationalPegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, [filgrastim]. … [A187631] Due to the relatively short circulating half-life of filgrastim, a 20 kDa PEG moiety was covalently conjugated to the N-terminus of filgrastim (at the methionine residue) to develop longer-acting
Categories: Compounds used in a research, industrial, or household settingSynonyms: PEG-G-CSF, Pegylated G-CSFRisankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigationalRisankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). … [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.
Products: Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, SKYRİZİ 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETTolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresolPovidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnThe clinical effectiveness of [DB06812] on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.
Mixtures: Leader Artificial Tears 15 mL, Premier Value Eye Drops MtCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingBivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalBivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. … It is administered intravenously.
Products: OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 10 ADET, OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 1 ADETFludarabine
go.drugbank.com/drugs/DB01073ApprovedInvestigationalFludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Synonyms: 2-F-ARAA, 2-fluoro ARA-ACategories: DNA (Cytosine-5-)-Methyltransferases, antagonists & inhibitors, Heterocyclic Compounds, 2-RingPalivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalSynagis is a composite of human (95%) and murine (5%) antibody sequences. … Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)
Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodyProducts: SYNAGIS® 50 MG, SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADETLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigational[A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
Mixtures: Dg Health Anti Diarrheal Anti GasCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigational[T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg. … [L2831] It is also considered as an active ingredient in over-the-counter products.[L1113]
Mixtures: Q-10 Plus, Cal-mag TabletProducts: MAGGZİUM 400 MG ORAL ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 50 ADET, Magnesium 150 mgPantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationalat the secretory surface of gastric parietal cell. … It can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [amoxicillin], [clarithromycin], and [metronidazole], for example.
Mixtures: OCAM® DUO.Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors