Search
Calcium polycarbophil
go.drugbank.com/drugs/DB14684ApprovedThis drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea. … Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali.
Categories: Drugs for ConstipationPhenindamine
go.drugbank.com/drugs/DB01619ApprovedAntihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. … Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body.
Categories: Antihistamines for Systemic UseAmbrisentan
go.drugbank.com/drugs/DB06403ApprovedInvestigationalAmbrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. … As an endothelin receptor antagonist, Ambrisentan prevents endogenous endothelin peptide from constricting the muscles in blood vessels, allowing them to relax and permit a reduction in blood pressure.
Categories: Antihypertensives for Pulmonary Arterial Hypertension, Endothelin Receptor AntagonistsStreptococcus pneumoniae type 3 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10321ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: PREVENAR 13 SUSPENSION FOR INJECTIONCarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigational[A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia, Europe, and South America. … [L32383] Several licenses for this drug were withdrawn following serious and fatal paradoxical effects after carbocisteine therapy in children; respiratory dress, dyspnea, and cough aggravation were
Type II Hyperlipidaemia
go.drugbank.com/conditions/DBCOND0040511Drugs: NiacinSynonyms: LDL receptor disorder, LDL - Low density lipoprotein receptor disorderPeginterferon beta-1a
go.drugbank.com/drugs/DB09122ApprovedInvestigational[A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing forms of MS. … Symptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings.
Golodirsen
go.drugbank.com/drugs/DB15593ApprovedInvestigationalThis is an X-linked condition leading to progressive muscle degeneration that begins in early childhood, rendering many patients wheelchair-bound by age 12. … [L10755,L10758] Golodirsen was initially rejected for FDA approval over concerns about its potential renal toxicity, however, clinical trials did not show significant toxicity.[L10755]
Tisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigationalIt is also being investigated for the combination use with other chemotherapeutic agents for recurrent or metastatic cervical cancer.[A238924] … This is the first and only approved antibody-drug conjugate for this therapeutic indication.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPD-0299685
go.drugbank.com/drugs/DB15264InvestigationalPD-0299685 is under investigation in clinical trial NCT00314964 (Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause).