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Displaying results 2931 - 2940 of 10000 in total
  1. Target

    Thioredoxin reductase 1, cytoplasmic

    go.drugbank.com/bio_entities/BE0001979
    TargetEnzymeHumans

    Reduces disulfide protein thioredoxin (Trx) to its dithiol-containing form (PubMed:8577704). Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. A selenocysteine residue at the C-t...

    Synonyms: Gene associated with retinoic and IFN-induced mortality 12 protein, Gene associated with retinoic and interferon-induced mortality 12 protein
  2. Drug

    Masitinib

    go.drugbank.com/drugs/DB11526
    InvestigationalVet approved

    Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

    Synonyms: 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDECategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Belotecan

    go.drugbank.com/drugs/DB12459
    Investigational

    Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer.

    Categories: Topoisomerase I Inhibitors, Topoisomerase 1 (TOP1) inhibitors
  4. Drug

    Roluperidone

    go.drugbank.com/drugs/DB13080
    Investigational

    Roluperidone has been used in trials studying the treatment of Schizophrenia.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists
  5. Drug

    BMS-690514

    go.drugbank.com/drugs/DB11665
    Investigational

    BMS-690514 has been investigated for the treatment of Breast Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Carnosine

    go.drugbank.com/drugs/DB11695
    Investigational

    Carnosine has been investigated for the treatment of Gulf War Illness.

    Synonyms: L-Carnosine
  7. Drug

    Danusertib

    go.drugbank.com/drugs/DB11778
    Investigational

    Danusertib has been used in trials studying the treatment of Leukemia.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Arhalofenate

    go.drugbank.com/drugs/DB11811
    Investigational

    Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia.

  9. Drug

    Methyl isocyanate

    go.drugbank.com/drugs/DB12765
    Investigational

    Methyl isocyanate has been investigated for the treatment of Nosocomial Pneumonia.

  10. Drug

    Laninamivir

    go.drugbank.com/drugs/DB12791
    Investigational

    Laninamivir has been used in trials studying the treatment of Influenza.

    Categories: Heterocyclic Compounds, 1-Ring