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Displaying results 2941 - 2950 of 10000 in total
  1. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. … Its hyperactivity and enhanced signalling pathways can be observed in inflammatory diseases where it activates further pro-inflammatory cascades.

    Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERProducts: REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED PEN, REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED SYRINGE
  2. Drug

    Ziritaxestat

    go.drugbank.com/drugs/DB15403
    Investigational

    Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)-(methyl)amino)-4-(4-fluorophenyl)-thiazole-5-carbonitrile
  3. Drug

    Estramustine

    go.drugbank.com/drugs/DB01196
    ApprovedWithdrawn

    A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

    Synonyms: Estradiol 3-(N,N-bis(2-chloroethyl)carbamate), 17β-Estradiol 3-(bis(2-chloroethyl)carbamate)Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  4. Drug

    Eletriptan

    go.drugbank.com/drugs/DB00216
    ApprovedInvestigational

    Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.

    Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor AgonistsProducts: Eletop 20 mg-Filmtabletten, Relpax 20 mg - Filmtabletten
  5. Drug

    1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane

    go.drugbank.com/drugs/DB02572
    Experimental

    Synonyms: 1,3-bis-([3-[3-[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-propoxy-ethoxy-ethoxy]-propyl-]amino-carbonyloxy)-2-amino-propane
  6. Drug

    Dexrazoxane

    go.drugbank.com/drugs/DB00380
    ApprovedInvestigationalWithdrawn

    It appears to inhibit formation of a toxic iron-anthracycline complex.

    Synonyms: 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione, 2, 6-Piperazinedione, 4,4'-propylenedi-, (P)- (8CI)Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  7. Drug

    Methoxy polyethylene glycol-epoetin beta

    go.drugbank.com/drugs/DB09107
    ApprovedInvestigational

    Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.

    Categories: Compounds used in a research, industrial, or household settingProducts: MIRCERA 50 UG/0.3 ML, MIRCERA® SOLUCION INYECTABLE JERINGA PRELLENADA 50 MCG / 0.3 ML
  8. Drug

    BCG vaccine

    go.drugbank.com/drugs/DB12768
    ApprovedInvestigationalWithdrawn

    BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.

    Products: BCG CULTURE SSI 30 MG 4 VIAL, CALGEVAX-BCG 11.25 MG INTRAVEZIKAL ENJEKSIYON IÇIN LIYOFILIZE TOZ IÇEREN AMPUL, 10 ADET
  9. Drug

    Cefalotin

    go.drugbank.com/drugs/DB00456
    ApprovedVet approvedWithdrawn

    Cefalotin is a cephalosporin antibiotic.

    Synonyms: CET, 7-(Thiophene-2-acetamido)cephalosporinCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Alogliptin

    go.drugbank.com/drugs/DB06203
    ApprovedInvestigational

    FDA approved January 25, 2013. … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.

    Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates