BCG vaccine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

BCG vaccine is a vaccine indicated in the prevention of tuberculosis and the treatment of non-invasive urothelial bladder cancer.

Generic Name
BCG vaccine
DrugBank Accession Number
DB12768
Background

BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Attenuated
Synonyms
  • Bacillus calmette-guerin live antigen, unspecified substrain
  • Bacillus Calmette–Guérin (BCG) vaccine
  • BCG
  • BCG vaccine

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Abacavir.
AbataceptThe risk or severity of infection can be increased when BCG vaccine is combined with Abatacept.
Acetic acidThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acetic acid.
Acetyl sulfisoxazoleThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acetyl sulfisoxazole.
AcyclovirThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acyclovir.
AdalimumabThe risk or severity of infection can be increased when BCG vaccine is combined with Adalimumab.
Adefovir dipivoxilThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Adefovir dipivoxil.
AldesleukinThe risk or severity of infection can be increased when BCG vaccine is combined with Aldesleukin.
AlefaceptThe risk or severity of infection can be increased when BCG vaccine is combined with Alefacept.
AlemtuzumabThe risk or severity of infection can be increased when BCG vaccine is combined with Alemtuzumab.
Interactions
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Food Interactions
Not Available

Products

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Categories

ATC Codes
L03AX03 — Bcg vaccine
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
XZQ806VFEO
CAS number
Not Available

References

General References
  1. TITCK Product Information: Calgevax-BCG (BCG for immunotherapy) powder for intravesical injection [Link]
  2. TITCK Product Information: SII-BCG (BCG vaccine, live, attenuated) powder for suspension for intradermal injection [Link]
PubChem Substance
347911376
RxNav
1344
Wikipedia
BCG_vaccine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingPreventionCoronavirus Disease 2019 (COVID‑19)1
4CompletedBasic ScienceAdverse Reaction to Vaccine / Heterologous Immunity / Infant Morbidity / Mortality, Infant / Trained Immunity / Vaccine Reaction1
4CompletedDiagnosticTuberculosis (TB)1
4CompletedPreventionBCG Infection / Immune Response / Vaccine Reaction1
4CompletedPreventionChronic Obstructive Pulmonary Disease (COPD) / Coronary Heart Disease (CHD) / Coronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Virus Diseases1
4CompletedPreventionClinical / Intervention / Prospective / Single-blind / Trial1
4CompletedPreventionTuberculosis (TB)1
4RecruitingPreventionAbsenteeism / Coronavirus Disease 2019 (COVID‑19) / Morbidity1
4RecruitingPreventionBCG Vaccination Reaction / Mother-Infant Interaction / Rubeola / Vaccine Preventable Disease1
4RecruitingPreventionBCG / Mortality, Infant1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntravesical
Powder, for solutionIntravesical
Powder, for suspensionIntravesical
Injection, powder, lyophilized, for solutionIntravesical
Injection, powder, for suspensionIntradermal
PowderIntravesical
Injection, powder, lyophilized, for solutionIntradermal
InjectionIntradermal
Injection, powder, lyophilized, for suspensionIntravesical
Injection, powder, for solutionIntravesical
InjectionIntradermal81 mg/1vial
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 21, 2016 00:07 / Updated on June 12, 2021 10:54