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Displaying results 2961 - 2970 of 10000 in total
  1. Pathway

    De Novo Triacylglycerol Biosynthesis TG(20:0/15:0/18:3(9Z,12Z,15Z))

    smpdb.ca/view/SMP0018903
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  2. Pathway

    De Novo Triacylglycerol Biosynthesis TG(24:0/15:0/18:3(9Z,12Z,15Z))

    smpdb.ca/view/SMP0020108
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  3. Pathway

    De Novo Triacylglycerol Biosynthesis TG(15:0/24:1(15Z)/20:2(11Z,14Z))

    smpdb.ca/view/SMP0032727
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  4. Pathway

    De Novo Triacylglycerol Biosynthesis TG(24:1(15Z)/15:0/20:2(11Z,14Z))

    smpdb.ca/view/SMP0037071
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  5. Pathway

    Phosphatidylethanolamine Biosynthesis PE(15:0/20:4(6E,8Z,11Z,13E)-2OH(5S,15S))

    smpdb.ca/view/SMP0127146
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...

    Drugs: Choline · Serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine · Pyrophosphoric acid
  6. Drug

    Viltolarsen

    go.drugbank.com/drugs/DB15005
    ApprovedInvestigational

    Although corticosteroids are effective in slowing disease progression in both DMD and BMD patients, they do not address the underlying molecular pathogenesis. … A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by the production of shortened and partially functional dystrophin protein.

  7. Drug

    MK-0777

    go.drugbank.com/drugs/DB12238
    Investigational

    MK-0777 has been used in trials studying the treatment of Schizophrenia, Anxiety Disorder, and Generalized Anxiety Disorder.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    ARCoV

    go.drugbank.com/drugs/DB15855
    Experimental

    SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. … Preclinical studies in mice and non-human primates has shown that intramuscular administration of ARCoV elicited a Th1-biased cellular response and robust antibodies against SARS-CoV-2[A220048].

  9. Drug

    Melphalan flufenamide

    go.drugbank.com/drugs/DB16627
    ApprovedWithdrawn

    [A230123] _In vitro_ models show that melphalan is 10 to hundreds of times more potent than melphalan. … Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan].

  10. Drug

    Avdoralimab

    go.drugbank.com/drugs/DB16392
    Investigational

    Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection).