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(5Z,7E,9)-decatrien-2-one
go.drugbank.com/drugs/DB15619InvestigationalSimilar to [(5E,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116]
Synonyms: (5Z,7E,9)-decatrien-2-oneInolimomab
go.drugbank.com/drugs/DB15628InvestigationalInolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385]
Synonyms: Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain), disulfide with mouse monoclonal B-B10 kappa-chain, dimerCategories: Receptors, Interleukin-2Garadacimab
go.drugbank.com/drugs/DB15629ApprovedGaradacimab is a fully human monoclonal antibody targeted against activated factor XII. … [L53283] It was developed by CSL Behring for use as a prophylactic agent in patients with hereditary angioedema (HAE), a rare autosomal dominant disorder that results in acute episodes of angioedema.
Glumetinib
go.drugbank.com/drugs/DB15630InvestigationalGlumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).
Synonyms: 6-(1-methyl-1h-pyrazol-4-yl)-1-((6-(1-methyl-1h-pyrazol-4-yl)imidazo(1,2-a)pyridin-3-yl)sulfonyl)-1h-pyrazolo(4,3-b)pyridineCategories: Heterocyclic Compounds, 1-RingZalifrelimab
go.drugbank.com/drugs/DB15632InvestigationalZalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Synonyms: A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4), Immunoglobulin G1-kappa, anti-(homo sapiens CTLA4 (cytotoxic tlymphocyte-associated protein 4, cd152))Temelimab
go.drugbank.com/drugs/DB15634InvestigationalTemelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Categories: Recombinant Humanized IgG4 Monoclonal Antibody Against pHERV-W Envelope ProteinFluzoparib
go.drugbank.com/drugs/DB15637InvestigationalFluzoparib is under investigation in clinical trial NCT03863860 (A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients).
Categories: Heterocyclic Compounds, 1-RingDihydromyricetin
go.drugbank.com/drugs/DB15645InvestigationalDihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingUlotaront
go.drugbank.com/drugs/DB15665InvestigationalSEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. … Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesGusacitinib
go.drugbank.com/drugs/DB15670InvestigationalGusacitinib is under investigation in clinical trial NCT02550678 (A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma).
Synonyms: 1-(4-(4-(4-HYDROXY-PIPERIDIN-1-YL)-PHENYLAMINO)-5-OXO-5,6-DIHYDRO-PYRIMIDO(4,5-D)PYRIDAZIN-2-YL)-PIPERIDIN-4-YL-ACETONITRILECategories: Heterocyclic Compounds, 1-Ring