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Displaying results 21 - 30 of 149866 in total
  1. Drug

    Fibrinogen human

    go.drugbank.com/drugs/DB09222
    ApprovedInvestigational

    Fibrinogen concentrate (human) is a hematological agent. It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting. … It is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin.

    Synonyms: Coagulation Factor I, Factor I humanMixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml, EVICEL Fibrin Sealant (Human)
  2. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor … is a fully recombinant factor VIII-Fc fusion protein which has an extended half-life compared with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1, a long-lived

    Categories: Blood Coagulation Factors, Recombinant ProteinsSynonyms: Human factor VIII, recombinant B-domain deleted, Antihemphilic factor, recombinant human B-domain deleted
  3. Drug

    Protein C

    go.drugbank.com/drugs/DB11312
    ApprovedInvestigational

    APC exerts its effect by inactivating essential components of the coagulation cascade (specifically factors V and VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot … Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade.

    Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, Octaplex Powder and Solvent for Solution for InfusionCategories: Blood Coagulation Factor Inhibitors, Decreased Coagulation Factor Activity
  4. Drug

    Benzyl alcohol

    go.drugbank.com/drugs/DB06770
    ApprovedInvestigational

    Mixtures: ZOLBENE CREMA TOPICA (CALAMINA 5% + OXIDO DE ZINC 5% + ALCOHOL BENCILICO 1%), Hand SanitizerCategories: benzyl alcohol, Scabicides, Insecticides and Repellents
  5. Drug

    Rurioctocog alfa pegol

    go.drugbank.com/drugs/DB16007
    ApprovedInvestigational

    Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. … [A245149] Hemophilia A is the most common inherited bleeding disorder leading to deficiency of factor VIII, which is caused by defects in the F8C gene that encodes coagulation factor VIII.

    Categories: Blood Coagulation Factors, Recombinant ProteinsSynonyms: Antihemophilic factor, pegylated (mw 20000) human sequence recombinant, PEGylated Recombinant Factor VIII
  6. Drug

    Susoctocog alfa

    go.drugbank.com/drugs/DB11606
    ApprovedInvestigational

    The recombinant porcine sequence allows less susceptibility to inactivation by circulating human factor VIII antibodies. … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this procoagulant protein.

    Categories: Blood Coagulation Factors, Blood and Blood Forming OrgansSynonyms: RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 CELLS: DES-(753-1418)-BLOOD-COAGULATION FACTOR VIII (PROCOAGULANT COMPONENT) SUS SCROFA, GLYCOSYLATED, Antihemophilic factor (recombinant) porcine sequence
  7. Drug

    Cetyl alcohol

    go.drugbank.com/drugs/DB09494
    Approved

    Cetyl alcohol is present in a waxy white powder or flake form at room temperature, and is insoluble in water and soluble in alcohols and oils [A32209]. … Discovered by Chevrenl in 1913, cetyl alcohol is one of the oldest known long-chain alcohol [A32209]. It may be contained in cosmetic and personal care products such as shampoos, creams and lotions.

    Categories: AlcoholsSynonyms: palmityl alcohol
  8. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons.

    Categories: Recombinant Human Insulin-like Growth Factor-1, Human Insulin-like Growth Factor AnalogsSynonyms: RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I, INSULIN-LIKE GROWTH FACTOR I (HUMAN)
  9. Drug

    Recombinant Factor XIII (human)

    go.drugbank.com/drugs/DB17729
    Experimental

    Synonyms: Recombinant Factor XIII (human)
  10. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.

    Synonyms: Polyvinyl alcohol, Alcohol polivinílicoMixtures: i-Drops ARTIFICIAL TEARS