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Displaying results 21 - 27 of 27 in total
  1. Pathway

    Efavirenz Anti-Viral Action Pathway

    smpdb.ca/view/SMP0124983
    Drug action

    Efavirenz is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. When HIV infects a cell, the virus first binds and fuses with the cell, releasing its nucleocapsid containing its RNA...

    Drugs: Efavirenz
  2. Pathway

    Lamivudine Metabolism Pathway

    smpdb.ca/view/SMP0000649
    Drug metabolism

    Lamivudine (2'-deoxy-3'-thiacytidine, 3TC) is a pyrimidine analog reverse transcriptase enzyme inhibitor used to treat human immunodeficiency virus type I (HIV-1), HIV-2, and Hepatitis B. When metabolized to its active triphosphate form,...

    Drugs: ATP · Lamivudine · Magnesium cation · Uridine-5'-Diphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium · Pyrophosphoric acid
  3. Pathway

    Emtricitabine Action Pathway

    smpdb.ca/view/SMP0000741
    Drug action

    Emtricitabine (also known as FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) for treating HIV infection by inhibiting the transcriptase reversibly. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate so that...

    Drugs: Emtricitabine
  4. Pathway

    Rilpivirine Action Pathway

    smpdb.ca/view/SMP0000744
    Drug action

    Rilpivirine, sold as Edurant, is an antiretroviral drug that works as a non-nucleoside reverse transcriptase inhibitor (NNRTI) to treat HIV infections. NNRTI drugs work by entering the cell that HIV is present in, and binding to HIV's re...

    Drugs: Rilpivirine
  5. Pathway

    Lamivudine Anti-viral Action Pathway

    smpdb.ca/view/SMP0124937
    Drug action

    Lamivudine is a reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. It is a nucleoside reverse transcriptase inhibitor (NRTI) that targets HIV infected cells in the body. When HIV infects a cell, the virus first...

    Drugs: ATP · Lamivudine · Magnesium cation
  6. Pathway

    Prednisone Metabolism Pathway

    smpdb.ca/view/SMP0125469
    Metabolic

    Prednisone is a synthetic, anti-inflammatory glucocorticoid that derives from cortisone. It is biologically inert and converted to prednisolone in the liver. The glucocorticoid receptor is located intracellularly within the cytoplasm and...

    Drugs: Prednisone · Prednisolone · Mesoheme · Rilpivirine
  7. Pathway

    Doravirine Action Pathway

    smpdb.ca/view/SMP0125908
    Drug action

    Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg).

    Drugs: Doravirine