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Displaying results 21 - 30 of 10000 in total
  1. Drug

    Unoprostone

    go.drugbank.com/drugs/DB06826
    ApprovedWithdrawn

    Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.

    Synonyms: 13,14-dihydro-15-keto-20-ethyl PGF2α
  2. Drug

    Docetaxel

    go.drugbank.com/drugs/DB01248
    ApprovedInvestigational

    [A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death.

    Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelProducts: DOCETAXEL 10 MG/ ML, HOSPIRA DOCETAXEL INJECTION (10 MG/ML)
  3. Drug

    Promethazine

    go.drugbank.com/drugs/DB01069
    ApprovedInvestigational

    [A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29 March 1951.[A190177,L4000]

    Mixtures: ARTU 100 ML SURUPSynonyms: 10-(2-Dimethylaminopropyl)phenothiazine, 10-[2-(dimethylamino)propyl]phenothiazine
  4. Drug

    Idebenone

    go.drugbank.com/drugs/DB09081
    ApprovedInvestigational

    Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).

    Mixtures: SALPEZIL 90/10 MG FILM KAPLI TABLET ,TABLET, 28 ADET, BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADETSynonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone
  5. Drug

    Profenamine

    go.drugbank.com/drugs/DB00392
    Approved

    Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism. It is sold under the trade name Parsitan in Canada. In the US, the marketing of profen...

    Synonyms: 10-[2-(diethylamino)-1-propyl]phenothiazine, N,N-diethyl-1-(10H-phenothiazin-10-yl)-2-propanamineProducts: Parsitan 50
  6. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … It was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376]

    Synonyms: 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)Products: Cabazitaxel EVER Pharma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung, Cabazitaxel ratiopharm 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung
  7. Drug

    Brexanolone

    go.drugbank.com/drugs/DB11859
    ApprovedInvestigational

    As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically for the treatment of postpar...

    Synonyms: allopregnan-3α-ol-20-one
  8. Drug

    Fluphenazine

    go.drugbank.com/drugs/DB00623
    Approved

    A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.

    Synonyms: 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol, 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazineProducts: PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 50 ADET, PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 100 ADET
  9. Drug

    Polysorbate 80

    go.drugbank.com/drugs/DB11063
    ApprovedInvestigational

    Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration or vaccinations. … Polysorbate 80 is a hydrophilic nonionic surfactant. It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops.

    Synonyms: polyoxyethylene-sorbitan-20 mono-oleate, Tween 80International brands: Tween-80
  10. Drug

    Kisspeptin-10

    go.drugbank.com/drugs/DB16210
    Investigational

    Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men).

    Synonyms: Kisspeptin-10, Kisspeptin-10 (human)