Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may... Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism.
- Mechanism
- Curator reviewed
Propiomazine acts as an antagonist of dopamine 1, 2, and 4 receptors, serotonin (5-HT) receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors. Its main use as a sedative is due to its antihistamine effect.
- Primary indication
- Propiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia.Curator reviewed
- Formula / weight
- C20H24N2OS · 340.482 g/mol (avg)
- Code names
- CB 1678 · Wy 1359
Resolves to
UVOIBTBFPOZKGP-UHFFFAOYSA-NSMILESCCC(=O)C1=CC2=C(SC3=CC=CC=C3N2CC(C)N(C)C)C=C1What you can answer from here — as of September 23, 2026
Which drugs share a target with Propiomazine, and which of those have an active Phase 3 trial?
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