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Propiomazine
go.drugbank.com/drugs/DB00777ApprovedStructurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors.
Categories: Adrenergic alpha-1 Receptor AntagonistsSynonyms: 10-(2-Dimethylaminopropyl)-2-propionylphenothiazine, 2-Propionyl-10-(2-(dimethylamino)propyl)phenothiazineDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death. … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676]
Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelProducts: DOCETAXEL 10 MG/ ML, HOSPIRA DOCETAXEL INJECTION (10 MG/ML)Promethazine
go.drugbank.com/drugs/DB01069ApprovedInvestigational[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29 March 1951.[A190177,L4000] … Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946.
Mixtures: ARTU 100 ML SURUPSynonyms: 10-(2-Dimethylaminopropyl)phenothiazine, 10-[2-(dimethylamino)propyl]phenothiazineIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalIdebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). … It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and consequently protects
Mixtures: SALPEZIL 90/10 MG FILM KAPLI TABLET ,TABLET, 28 ADET, BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADETSynonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinoneProfenamine
go.drugbank.com/drugs/DB00392ApprovedProfenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism. … [L46812] In the US, the marketing of profenamine has been discontinued.[L46817]
Synonyms: 10-[2-(diethylamino)-1-propyl]phenothiazine, N,N-diethyl-1-(10H-phenothiazin-10-yl)-2-propanamineProducts: Parsitan 50Cabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalCabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … It was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376]
Synonyms: 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)Products: Cabazitaxel EVER Pharma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung, Cabazitaxel ratiopharm 10 mg/ml Konzentrat zur Herstellung einer InfusionslösungFluphenazine
go.drugbank.com/drugs/DB00623ApprovedA phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Synonyms: 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol, 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazineProducts: PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 50 ADET, PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 100 ADETBrexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalAs of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically … In particular, the use of brexanolone in treating PPD is surrounded with promise because it acts in part as a synthetic supplement for possible deficiencies in endogenous brexanolone (allopregnanolone)
Synonyms: allopregnan-3α-ol-20-onePolysorbate 80
go.drugbank.com/drugs/DB11063ApprovedInvestigationalPolysorbate 80 is a hydrophilic nonionic surfactant. It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops. … Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration or vaccinations.
Synonyms: polyoxyethylene-sorbitan-20 mono-oleate, Tween 80International brands: Tween-80Kisspeptin-10
go.drugbank.com/drugs/DB16210InvestigationalKisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men).
Synonyms: Kisspeptin-10, Kisspeptin-10 (human)