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Displaying results 21 - 30 of 10000 in total
  1. Drug

    Ibrutinib

    go.drugbank.com/drugs/DB09053
    ApprovedInvestigational

    [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November 2014. … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.

    Synonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
  2. Drug

    Norethisterone

    go.drugbank.com/drugs/DB00717
    ApprovedInvestigational

    [A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications … as an oral contraceptive until 1962.

    Mixtures: Tarina Fe 1/20 EQ, Tarina Fe 1/20 EQSynonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one
  3. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy. … It was initially granted FDA approval in 1982 and was the first emergency contraceptive containing only progesterone, showing high levels of efficacy and a lack of estrogenic adverse effects when compared

    Synonyms: (-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one, 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-oneMixtures: Aubra EQ, Chateal EQ
  4. Drug

    AEF0117

    go.drugbank.com/drugs/DB27675
    Investigational

    AEF0117 is under investigation in clinical trial NCT05554926 (Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects).

    Synonyms: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one, 3β-(4-methoxybenzyloxy)pregn-5-en-20-one
  5. Drug

    1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE

    go.drugbank.com/drugs/DB08085
    Experimental

    Synonyms: 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE
  6. Drug

    Isoeugenol

    go.drugbank.com/drugs/DB14188
    Approved

    Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang.

    Synonyms: 2-methoxy-4-(prop-1-en-1-yl)phenol
  7. Drug

    beta-Sitosterol

    go.drugbank.com/drugs/DB14038
    Investigational

    Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.

    Synonyms: (3β)-Stigmast-5-en-3-ol, (24R)-ethylcholest-5-en-3β-ol
  8. Drug

    Itruvone

    go.drugbank.com/drugs/DB21543
    Investigational

    Itruvone is under investigation in clinical trial NCT02322086 (A Phase 2 Study of Cellular and Immunologic Changes in the Skin of Subjects Receiving PH-10).

    Synonyms: Pregn-4-en-20-yn-3-one
  9. Drug

    Olesoxime

    go.drugbank.com/drugs/DB05185
    Investigational

    Olesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models.

    Synonyms: (EZ)-N-(CHOLEST-4-EN-3-YLIDENE)HYDROXYLAMINE, cholest-4-en-3-one, oxime
  10. Drug

    Solasodine

    go.drugbank.com/drugs/DB18813
    Investigational

    Synonyms: Solasod-5-en-3.beta.-ol, (3.beta.,22.alpha.,25r)-spirosol-5-en-3-ol