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Ibrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIt is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … [L45889] It is currently approved for the treatment of various conditions, such as chronic lymphocytic leukemia (CLL), Waldenström's Macroglobulinemia, and chronic graft versus host disease (cGVHD) in
Synonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneProducts: IMBRUVICA 140 mg film-coated tablets, IMBRUVICA 280 mg film-coated tabletsNorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigational[A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol … as an oral contraceptive until 1962.
Mixtures: Tarina Fe 1/20 EQ, Tarina Fe 1/20 EQSynonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-oneAEF0117
go.drugbank.com/drugs/DB27675InvestigationalAEF0117 is under investigation in clinical trial NCT05554926 (Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects).
Synonyms: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one, 3β-(4-methoxybenzyloxy)pregn-5-en-20-one1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE
go.drugbank.com/drugs/DB08085ExperimentalSynonyms: 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONEIsoeugenol
go.drugbank.com/drugs/DB14188ApprovedIsoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. … It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry [A34278].
Synonyms: 2-methoxy-4-(prop-1-en-1-yl)phenolEleuthero
go.drugbank.com/drugs/DB14303ApprovedInvestigationalEleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Et Maxim.) Maxim. Root, Acanthopanacis Senticosi Radix Et Rhizoma Seu Caulisbeta-Sitosterol
go.drugbank.com/drugs/DB14038InvestigationalActive fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.
Synonyms: (3β)-Stigmast-5-en-3-ol, (24R)-ethylcholest-5-en-3β-olItruvone
go.drugbank.com/drugs/DB21543InvestigationalItruvone is under investigation in clinical trial NCT02322086 (A Phase 2 Study of Cellular and Immunologic Changes in the Skin of Subjects Receiving PH-10).
Synonyms: Pregn-4-en-20-yn-3-oneVitamin A
go.drugbank.com/drugs/DB00162ApprovedInvestigationalNutraceuticalVet approvedDietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products. … Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the
Mixtures: Multivit Et Fer Ampoules Et Comprimes, Vitamines Et MinerauxCategories: Retinoids for Topical Use in Acne, Compounds used in a research, industrial, or household settingOlesoxime
go.drugbank.com/drugs/DB05185InvestigationalOlesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models. … For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]
Synonyms: (EZ)-N-(CHOLEST-4-EN-3-YLIDENE)HYDROXYLAMINE, cholest-4-en-3-one, oxime