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Displaying results 291 - 300 of 2828 in total
  1. Target

    GDP-fucose transporter 1

    go.drugbank.com/bio_entities/BE0018022
    TransporterHumans

    Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP. Involved in GDP-fucose import from the cytoplasm into the Golgi lumen

    Polypeptides: GDP-fucose transporter 1Function: GDP-fucose transmembrane transporter activity
  2. Drug

    Demplatin pegraglumer

    go.drugbank.com/drugs/DB14807
    Investigational

    Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).

    Synonyms: A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl linkagecisplatin is incorporated in polymeric micelles via polymer-metal complex formation with
  3. Target

    O-phosphoseryl-tRNA(Sec) selenium transferase

    go.drugbank.com/bio_entities/BE0002171
    TargetHumans

    Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

    Polypeptides: O-phosphoseryl-tRNA(Sec) selenium transferaseSynonyms: tRNA(Ser/Sec)-associated antigenic protein, Sec synthase
  4. Drug

    (1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose

    go.drugbank.com/drugs/DB04240
    Experimental

    Synonyms: 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE
  5. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in the public in 1998 [A175732], continues to see

    Products: DYNA-SEX
  6. Drug

    Zinc mesoporphyrin

    go.drugbank.com/drugs/DB17694
    Experimental

    Synonyms: 21h,23h-porphine-2,18-dipropanoic acid, 7,12-diethyl-3,8,13,17-tetramethyl-, zinc complex
  7. Drug

    Benzalkonium

    go.drugbank.com/drugs/DB11105
    ApprovedInvestigational

    Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA...

    Mixtures: ORA-SED JEL, Tieso RapidoProducts: Baby Essentials Gift Set, Sea Minerals Antibacterial
  8. Target

    Mitochondrial basic amino acids transporter

    go.drugbank.com/bio_entities/BE0000097
    TargetHumans

    Does not transport carnitine nor acylcarnitines (PubMed:24652292). Functions by both counter-exchange and uniport mechanisms (PubMed:24652292). … Mitochondrial transporter of arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine (PubMed:19287344, PubMed:24652292).

    Polypeptides: Mitochondrial basic amino acids transporterSynonyms: Mitochondrial ornithine transporter 3
  9. Target

    Choline transporter-like protein 1

    go.drugbank.com/bio_entities/BE0001059
    TransporterHumans

    Choline/H+ antiporter (PubMed:19357133, PubMed:23651124, PubMed:31855247, PubMed:33789160). Also acts as a high-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redis...

    Polypeptides: Choline transporter-like protein 1Function: choline transmembrane transporter activity
  10. Target

    Excitatory amino acid transporter 1

    go.drugbank.com/bio_entities/BE0001115
    TargetTransporterHumans

    Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). … Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940).

    Polypeptides: Excitatory amino acid transporter 1Synonyms: Sodium-dependent glutamate/aspartate transporter 1