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Drotaverine
go.drugbank.com/drugs/DB06751ApprovedWithdrawnDrotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). … [A7036] It also has been investigated in dysmenorrhea, abortion, [A231609] and augmentation of labour.
Categories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 InhibitorsBarzolvolimab
go.drugbank.com/drugs/DB18934InvestigationalBarzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Synonyms: Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-MusBeremagene geperpavec
go.drugbank.com/drugs/DB17831ApprovedInvestigational[L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component of the anchoring fibrils for dermal–epidermal cohesion. … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy.
Categories: Cellular and Gene TherapySynonyms: B-VEC, Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying)Loratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigationalLoratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Mixtures: VALKET-D ®, LORAMINE® R GRAGEASCategories: P-glycoprotein inhibitors, P-glycoprotein substratesDocusate
go.drugbank.com/drugs/DB11089ApprovedRecently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912]. … Still docusate is available in over-the-counter products as a common laxative.
Mixtures: Senna-S, Senexon-SProducts: H E B Stool Softener laxative, Doc Q LaceSelenium
go.drugbank.com/drugs/DB11135ApprovedInvestigationalVet approvedSelenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen
Mixtures: GNC Mega Teen, BLACKMORES teen multi for GUYS capsuleCategories: Compounds used in a research, industrial, or household settingPCO-371
go.drugbank.com/drugs/DB14946InvestigationalPCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).
Categories: Heterocyclic Compounds, 1-RingSynonyms: non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I, 2,4-IMIDAZOLIDINEDIONE, 1-(3,5-DIMETHYL-4-(2-((4-OXO-2-(4-(TRIFLUOROMETHOXY)PHENYL)-1,3,8-TRIAZASPIRO(4.5)DEC-1-EN-8-YL)SULFONYL)ETHYL)PHENYL)-5,5-DIMETHYL-Brenetafusp
go.drugbank.com/drugs/DB19441InvestigationalBrenetafusp is under investigation in clinical trial NCT04262466 (Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors).
Synonyms: Immunoglobulin, anti-(human CD3 antigen ε-chain) (human-Mus musculus single-chain Fv fragment VL-((GGGGS)4GGGS)-VH) fusion protein with peptide linker (GGGGS) fusion protein with T-cell receptor β chainPiretanide
go.drugbank.com/drugs/DB02925ApprovedPiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in
Mixtures: RAMIPRIL PIRETA 1A PHA 5/6, RAMIPRIL PIRETA 1A PHA 5/6Products: ARELIX 6, ARELIX MITE 3VEGFR 2 Kinase inhibitor I
go.drugbank.com/drugs/DB17061ExperimentalSynonyms: Vegf receptor 2 kinase inhibitor i, 3-(2,4-dimethyl-3-ethoxycarbonylpyrrol-5-methylidenyl)-2-indolinone