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Spironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalSpironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed pur...
Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 InhibitorsProducts: SPIRONOLACTON 100MG AAA PHFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigational[L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo or in combination with [doxazosin], an alpha-blocker.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Finasterid G.L. 5 mg - Filmtabletten, FINASTERIDE MYLAN GENERICSEnsulizole
go.drugbank.com/drugs/DB11115ApprovedEnsulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV ...
Mixtures: Protective Gel-cream Body SPF 20, Sundays Moderate Protec Bronz Gel Spf4Products: Hawaiian TroP.C.and A.tan Gel W.eX.S.S.4spfHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 1...
Mixtures: Mycozyl HC Cream GelCategories: P-glycoprotein inducers, P-glycoprotein substratesBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalBenzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain reli...
Mixtures: Difflam mouth gel, DIFFLAM MOUTH GELProducts: Tantum 5% Gel, TANTUM VERDE PGriseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersProducts: Fulvicin P/G 165, Fulvicin Pg Tab 330mgMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Pethidine HCl Fresenius PF 50mg/ml InjectionAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpat...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: AMIODARONE PH&T, AMIODARONE MYLAN GENERICSAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigationalAbiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis. Abiraterone was first ap...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Abirateron G.L. 500 mg-FilmtablettenVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalVerapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a m...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Verelan PM, Verapamil Hydrochloride PM