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Displaying results 2991 - 3000 of 7284 in total
  1. Drug

    Nestifylline

    go.drugbank.com/drugs/DB19989
    Experimental

    Nestifylline has a monoisotopic molecular weight of 298.06 Da. … Nestifylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Nestifylline is a N-methylated xanthine derivative.

  2. Drug

    Peralopride

    go.drugbank.com/drugs/DB20064
    Experimental

    Peralopride has a monoisotopic molecular weight of 403.13 Da. … Peralopride is a small molecule drug. The usage of the INN stem '-pride' in the name indicates that Peralopride is a sulpiride derivative and analogue.

  3. Drug

    Torbafylline

    go.drugbank.com/drugs/DB20095
    Experimental

    Torbafylline has a monoisotopic molecular weight of 338.2 Da. … Torbafylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Torbafylline is a N-methylated xanthine derivative.

  4. Drug

    Rociclovir

    go.drugbank.com/drugs/DB20123
    Experimental

    Rociclovir has a monoisotopic molecular weight of 323.2 Da. … Rociclovir is a small molecule drug. The usage of the INN stem '-ciclovir' in the name indicates that Rociclovir is a antiviral, bicyclic heterocycle compound.

  5. Drug

    Orenasitecan

    go.drugbank.com/drugs/DB21718
    Experimental

    Orenasitecan has a monoisotopic molecular weight of 1470.58 Da. … Orenasitecan is a small molecule drug. The usage of the INN stem '-tecan' in the name indicates that Orenasitecan is a antineoplastic, topoisomerase I inhibitor.

  6. Drug

    Mocaciclib

    go.drugbank.com/drugs/DB21730
    Experimental

    Mocaciclib has a monoisotopic molecular weight of 609.3 Da. … Mocaciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Mocaciclib is a cyclin dependant kinase inhibitor.

  7. Drug

    Abrocitinib

    go.drugbank.com/drugs/DB14973
    ApprovedInvestigational

    including atopic dermatitis, a chronic inflammatory skin disease with complex pathogenesis. … [A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy.

  8. Drug

    Dacomitinib

    go.drugbank.com/drugs/DB11963
    ApprovedInvestigational

    [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index
  9. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609]. … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807].

    Mixtures: Cooper A.R., GOTABIOTIC D
  10. Drug

    Estradiol dienanthate

    go.drugbank.com/drugs/DB13955
    ApprovedVet approvedWithdrawn

    Estradiol Dienanthate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … First-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a chance to enter systemic circulation and exert its estrogenic effects [A12102].