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Cabergoline
go.drugbank.com/drugs/DB00248ApprovedInvestigationalCabergoline possesses potent agonist activity on dopamine D2 receptors. … Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome.
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AgonistsSynonyms: 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea, (8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamideFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approved[A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily. … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamideChlorphenesin carbamate
go.drugbank.com/drugs/DB14656ApprovedInvestigationalVet approvedWithdrawnSynonyms: 3-(p-chlorophenoxy)-2-hydroxypropyl carbamate, carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl esterPhenylacetic acid
go.drugbank.com/drugs/DB09269ApprovedPhenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor.
Synonyms: 2-PHENYLACETIC ACID, ANTINEOPLASTON AS 2-1 COMPONENT PHENYLACETIC ACIDOzekibart
go.drugbank.com/drugs/DB18675InvestigationalOzekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Synonyms: Immunoglobulin, anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) fusion protein with peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor, 5) (human-Lama glama clone IF5 single-domain VHHTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Synonyms: N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine, (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acidProducts: TIROSTU 12.5 MG/50 ML IV KONSANTRE İNFÜZYONLUK ÇÖZELTİ, 1 ADET, AGRABAN 12.5 MG/50 ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 FLAKONVorasidenib
go.drugbank.com/drugs/DB17097ApprovedInvestigational[A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms. … Vorasidenib is a first-in-class dual isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor.
Categories: Isocitrate Dehydrogenase 2 Inhibitor, Isocitrate dehydrogenase-2 (IDH2) InhibitorsSynonyms: 1,3,5-triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-n2,n4-bis((1r)-2,2,2-trifluoro-1-methylethyl)-1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA
go.drugbank.com/drugs/DB07622ExperimentalSynonyms: 1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID
go.drugbank.com/drugs/DB04656ExperimentalSynonyms: 1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene
go.drugbank.com/drugs/DB02200ExperimentalSynonyms: 3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene